Method and apparatus for treatment of gastro-esophageal reflux disease (GERD)

• US 20060229685A1
• Filed: 06/09/2006
• Published: 10/12/2006
• Est. Priority Date: 02/03/2003
• Status: Abandoned Application

• Current Assignee: ReShape LifeSciences, Inc.
• Original Assignee: ReShape LifeSciences, Inc.
• Inventors: Evnin, Luke B., Knudson, Mark B., Tweden, Katherine S., Conrad, Timothy R.
• Application Number:
  US11/450,202
• Publication Number:
  US 20060229685A1
• Time in Patent Office: Days
• US Class Current: 607/40
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/321 Electromedical belts
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36053 adapted for vagal stimulation A61N1/36114 takes precedence
• CPC Class Codes: A61N 1/3606 adapted for a particular treatment
• CPC Class Codes: A61N 1/36071 Pain

Abstract

GERD is treated through a method and apparatus of stimulating the body organ to accelerate a discharge of contents from the duodenum of the patient to thereby encourage discharge of contents from the stomach of the patient across the pyloric valve and into the duodenum.

Claims

1. A method for treating gastro-esophageal reflux disease (GERD) of a patient comprising:

treating a body organ to accelerate a discharge of contents through at least a portion of a small intestine of the patient to thereby encourage discharge of contents from a stomach of the patient across a pyloric valve of the patient and into said small intestine.

2. A method according to claim 1 wherein said portion is a duodenum of said patient.

3. A method according to claim 1 wherein said treating is a stimulation selected to increase a pH of said contents of said portion of said small intestine.

4. A method according to claim 1 wherein said treating is a stimulation selected to decrease an osmolality of said contents of said portion of said small intestine.

5. A method according to claim 1 wherein said organ is a pancreas of said patient and said treating is a stimulation of said organ selected to stimulate delivery of an exocrine secretion from said pancreas to said portion of said small intestine.

6. A method according to claim 5 wherein said pancreas is stimulated directly.

7. A method according to claim 5 wherein said pancreas is indirectly stimulated by stimulating at least a nerve of said pancreas.

8. A method according to claim 5 wherein said stimulation is initiated by said patient.

9. A method according to claim 5 wherein said stimulation is initiated by a controller operatively connected to stimulating electrodes and having an input operatively connected to a sensor.

10. A method according to claim 9 wherein said sensor senses a pH level of said portion of said small intestine.

11. A method according to claim 9 wherein said sensor senses a degree of filling of said portion of said small intestine.

12. A method according to claim 9 wherein said sensor senses a degree of osmolality within said portion of said small intestine.

13. A method according to claim 9 wherein said sensor senses a degree of motility within said portion of said small intestine.

14. A method according to claim 1 wherein said treatment includes delivery of a paralyzing agent to said pyloric valve.

15. A method according to claim 14 wherein said delivery is done in conjunction with agents to manage acidity of a content of said portion of said small intestine.

16. A method according to claim 15 wherein said agents are selected from a group including H₂ antagonists and PPI'"'"'s.

17. A method according to claim 5 wherein said stimulation is an electrical stimulation.

18. A method according to claim 17 wherein said stimulation is at a frequency selected to encourage exocrine secretion without excess endocrine secretion.

19. A method according to claim 1 wherein said treating is a stimulation selected to encourage bile delivery to the portion of said small intestine.

20. A method according to claim 1, wherein the body organ is a duodenum of said patient.