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Biomarkers for predicting prostate cancer progression

  • US 20060234259A1
  • Filed: 02/24/2006
  • Published: 10/19/2006
  • Est. Priority Date: 02/25/2005
  • Status: Active Grant
First Claim
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1. A method for characterizing prostate tissue in a subject, comprising steps of:

  • providing a sample of prostate tissue obtained from the subject; and

    determining the levels of expression of a set of genes selected from the group consisting of ABP280 (FLNA), AMACR, AR, BM28, BUB3, CaMKK, CASPASE3, CDK7, DYNAMIN, E2F1, E-CADHERIN, EXPORTIN, EZH2, FAS, GAS7, GS28, ICBP90, ITGA5, JAGGED1, JAM1, KANADAPTIN, KLF6, KRIP1, LAP2, MCAM, MIB1 (MKI67), MTA1, MUC1, MYOSIN-VI, P27, P63, PAXILLIN, PLCLN, PSA(KLK3), RAB27, RBBP, RIN1, SAPKalpha, TPD52, XIAP, and ZAG, to obtain a gene expression pattern for the prostate tissue sample, thereby characterizing the prostate tissue.

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