Ocular inlay with locator

• US 20060235428A1
• Filed: 04/14/2005
• Published: 10/19/2006
• Est. Priority Date: 04/14/2005
• Status: Abandoned Application

• Current Assignee: Acufocus, Inc. (Bausch Health Cos., Inc.)
• Original Assignee: Acufocus, Inc. (Bausch Health Cos., Inc.)
• Inventors: Silvestrini, Thomas A.
• Application Number:
  US11/106,040
• Publication Number:
  US 20060235428A1
• Time in Patent Office: Days
• US Class Current: 606/107
• CPC Class Codes: A61F 2/145 Corneal inlays, onlays, or lenses for refractive correction
• CPC Class Codes: A61F 2/15 Implant having one or more holes, e.g. for nutrient transport, for facilitating handling
• CPC Class Codes: A61F 2/16 Intraocular lenses
• CPC Class Codes: A61F 2250/0097 Visible markings, e.g. indicia
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/00834 Inlays; Onlays; Intraocular lenses [IOL]

Abstract

A therapeutic ocular inlay for treatment of one or more vision defects including a locator structure or depth marker to facilitate location of the inlay post-implant. The locator structure or marker extends at least partially outside a pupil region. The depth or layer at which the inlay is implanted can be determined by locating the depth marker without requiring incisions with the pupil region. The locator structure can be substantially invisible under casual observation, however can be provided with enhanced optical contrast characteristics under selected viewing conditions. The locator is thus unobtrusive, however can be readily located in a clinical setting, for example with artificial UV illumination. The locator can be connected to, e.g., integrally formed with, the inlay or may be a separate component provided in combination with the inlay.

Claims

1. An implantable ocular device comprising:

a therapeutic inlay configured to be implanted at a selected region of a patient'"'"'s eye at least partially within a pupil region of the eye to provide therapy for at least one vision deficiency; and

a locator structure configured to be implanted within the eye and to extend at least partially outside of the pupil region of the eye to be accessible post-implant from outside the pupil region.

2. The implantable ocular device of claim 1, wherein the selected region comprises a selected layer of a cornea.

3. The implantable ocular device of claim 1, wherein the inlay provides therapy for presbyopia.

4. The implantable ocular device of claim 3, wherein the inlay is at least partially opaque.

5. The implantable ocular device of claim 1, wherein at least part of the locator structure is substantially transparent and colorless.

6. The implantable ocular device of claim 1, wherein the locator structure is connected to the inlay.

7. The implantable ocular device of claim 6, wherein the locator structure further comprises a retrieval structure such that a force applied to the retrieval structure induces the device to be withdrawn from the selected region of the eye.

8. The implantable ocular device of claim 1, wherein at least a portion of the locator structure is provided with an observable tint to provide increased optical contrast with adjacent eye tissue.

9. The implantable ocular device of claim 8, wherein the tint of the locator structure provides increased contrast with adjacent eye tissue under incident electro-magnetic radiation of selected wavelengths outside the visible light range.

10. The implantable ocular device of claim 1, wherein, in an implanted condition, the locator structure is substantially invisible under normal viewing conditions.

11. A method of providing vision therapy comprising;

implanting a first therapeutic inlay in a patient'"'"'s eye at a selected level, the first inlay having a therapy region configured to provide therapy for at least one vision deficiency; and

implanting a first locator structure at the selected level such that the selected level can be identified at a later time by accessing at least a portion of the first locator structure at a location of the patient'"'"'s eye outside of the therapy region.

12. The method of claim 11, further comprising

accessing at least a portion of the first locator structure to locate the selected level;

and

removing the first therapeutic inlay.

13. The method of claim 12, further comprising:

implanting a second therapeutic inlay in the patient'"'"'s eye at the selected level, the second inlay having a therapy region configured to provide therapy for at least one vision deficiency; and

implanting a second locator structure at the selected level such that the selected level can be identified at a later time by accessing at least a portion of the locator structure at a location of the patient'"'"'s eye outside of the therapy region.

14. The method of claim 11, wherein the first locator structure comprises a retrieval structure, the method further comprising:

engaging a instrument with the retrieval structure; and

applying a force through the instrument to the retrieval structure to withdraw the inlay from the selected level.

15. The method of claim 11, further comprising

illuminating the first locator structure with electromagnetic radiation of selected wavelengths to induce at least a portion of the first locator structure to present enhanced contrast against eye tissue adjacent the first locator structure.

16. An inlay for implantation in a cornea of a patient between a first corneal layer and a second corneal layer, the cornea having a pupil region, the inlay comprising:

a mask body having an outer periphery that substantially surrounds a transmissive central portion, the mask body comprising an anterior surface configured to reside adjacent the first corneal layer and a posterior surface configured to reside adjacent the second corneal layer, the mask body configured such that at least the transmissive central portion can be located in the pupil region of the cornea when the inlay is applied; and

a depth marker configured to be positioned between the first and second corneal layers outside the pupil region, the depth marker configured to indicate the location of the mask body.

17. The corneal inlay of claim 16, wherein the depth marker comprises an elongate member having a first end located adjacent to the outer periphery of the mask body and a second end opposite the first end.

18. The corneal inlay of claim 17, wherein the first end is coupled with the mask body.

19. The corneal inlay of claim 17, wherein the depth marker further comprises a visible portion adjacent the second end.

20. The corneal inlay of claim 19, wherein visible portion comprises a fluorescent dye.

21. The corneal inlay of claim 16, wherein the depth marker is configured to indicate the location of at least one of the first and second corneal layers.