Libraries and data structures of materials removed by debulking catheters

• US 20060236019A1
• Filed: 09/21/2005
• Published: 10/19/2006
• Est. Priority Date: 04/19/2005
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Foxhollow Technologies Incorporated (Medtronic Plc)
• Inventors: Simpson, John B., Soito, Angela
• Granted Patent: US 7,794,413 B2
• Time in Patent Office: Days
• US Class Current: 711/1
• CPC Class Codes: A61B 10/0096 Casings for storing test samples A61B10/0038 and A61B10/0045 take precedence; preservation of living parts of the human or animal body A01N1/02; containers for retaining a material to be analysed B01L3/50; containers for enzymology or microbiology C12M1/16; swab-sampler being part of enzymology or microbiology container C12M1/30
• CPC Class Codes: A61B 10/02 Instruments for taking cell samples or for biopsy A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48
• CPC Class Codes: A61B 10/0266 means for severing sample
• CPC Class Codes: A61B 10/04 Endoscopic instruments
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 17/320783 through side-hole, e.g. sliding or rotating cutter inside catheter
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61B 2017/320791 with cutter extending outside the cutting window
• CPC Class Codes: A61B 90/90 Identification means for patients or instruments, e.g. tags
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

Material removed by a debulking catheter from a body lumen can be preserved. Materials can be collected from many different patients and/or from multiple procedures on individual patients. Data which describe the properties or qualities of the removed material and/or the patient and/or the patient'"'"'s family or environment can be stored on computer readable media. The stored data can be used to draw correlations, to stratify groups of patients, to provide risk assessments, to provide diagnoses and/or prognoses. Further tests can be done on the stored materials at later times after the procedures have been completed.

Claims

1. One or more computer readable media having a data structure stored thereon, said data structure comprising:

a first data field comprising a value corresponding to a property of a first tissue sample excised from a vascular lumen of a patient;

a second data field comprising data identifying a patient.

2. The computer readable media of claim 1 further comprising:

a third data field comprising a value corresponding to cardiac health of the patient.

3. The computer readable media of claim 1 wherein the property is a level of a marker in the tissue.

4. The computer readable media of claim 1 wherein the property is composition of the tissue sample.

5. The computer readable media of claim 1 wherein the property is histologic characterization of the tissue.

6. The computer readable media of claim 1 wherein the property is an immunochemical characterization of the tissue.

7. The computer readable media of claim 1 wherein the property is a genomic characteristic.

8. The computer readable media of claim 1 wherein the property is level of a mRNA.

9. The computer readable media of claim 1 wherein the property is location of the vascular lumen from which the tissue was excised.

10. The computer readable media of claim 1 wherein the property is volume or mass of the excised tissue.

11. The computer readable media of claim 1 further comprising:

a fourth data field comprising a value corresponding to a characteristic of the patient'"'"'s blood.

12. The computer readable media of claim 11 wherein the patient'"'"'s blood was withdrawn at the time of or before tissue excision.

13. The computer readable media of claim 1 further comprising:

a fifth data field comprising a value corresponding to family history of the patient.

14. The computer readable media of claim 1 further comprising:

a sixth data field comprising a value corresponding to the patient'"'"'s medical history.

15. The computer readable media of claim 1 further comprising:

a seventh data field comprising a value corresponding to a property of a second tissue sample excised from a vascular lumen of the patient at a distinct time.

16. The computer readable media of claim 15 wherein the second tissue sample is excised from the same vascular lumen as the first tissue sample.

17. The computer readable media of claim 1 further comprising:

an eighth data field comprising a value corresponding to a property of a second tissue sample excised from distinct vascular lumen of the patient on the same day as the first tissue sample.

18. The computer readable media of claim 1 wherein said media are associated with one or more excised tissue samples in labeled storage containers, wherein the computer readable media comprise a ninth data field which comprises a value which links the labeled storage containers with a value in the second data field.

19. The computer readable media of claim 1 wherein said media are associated with one or more excised tissue samples in labeled storage containers, wherein the storage containers are labeled with a value in the second data field.

20. The computer readable media of claim 1 wherein said media are associated with one or more samples in labeled storage containers, wherein the one or more samples comprise a component extracted or processed from an excised vascular tissue from a vascular lumen of the patient, wherein the component is selected from the group consisting of DNA, RNA, cDNA, and protein, and wherein the computer readable media comprise a tenth data field which comprises a value which links the labeled storage containers with a value in the second data field.

21. The computer readable media of claim 1 wherein said media are associated with one or more samples in labeled storage containers, wherein the storage containers are labeled with a value in the second data field, wherein the samples comprise a component extracted or processed from an excised vascular tissue from a vascular lumen of the patient, wherein the component is selected from the group consisting of DNA, RNA, cDNA, and protein.