Interdigitated chemical sensors, and methods of making and using the same

• US 20060237310A1
• Filed: 04/26/2005
• Published: 10/26/2006
• Est. Priority Date: 04/26/2005
• Status: Active Grant

• Current Assignee: Seacoast Science Incorporated
• Original Assignee: Seacoast Science Incorporated
• Inventors: Patel, Sanjay V., Klaasen, Erno, Mlsna, Todd E.
• Granted Patent: US 7,837,844 B2
• Time in Patent Office: Days
• US Class Current: 204/400
• CPC Class Codes: G01N 27/226 Construction of measuring vessels; Electrodes therefor

Abstract

The present invention relates to the field of chemical detection. More specifically, the invention provides devices that can detect various target analytes (e.g., chemicals and/or biological materials) present in an environment by adsorption or absorption of the target analyte(s) to or in a chemical sensing material such that an electrical parameter (e.g., capacitance, resistance, etc.) of the chemical sensing material is altered in a manner detectable by circuitry associated with the sensing electrode pair coated with the chemical sensing material. Here, the sensing electrode pair(s) of the devices of the invention are suspended over an inert substrate via one or more posts used to space the electrodes from the substrate.

Claims

1. A sensing electrode pair, comprising:

a. a substrate;

b. a pair of spaced sensing electrodes elevated above the substrate, wherein one of the electrodes of the electrode pair is a drive electrode and the other electrode of the electrode pair is a sense electrode in electrical communication with the drive electrode, and wherein each of the drive electrode and sense electrode is elevated above the substrate by at least one post disposed between the substrate and the electrode so as to space the electrode from an upper surface of the substrate; and

c. a chemical sensing material disposed on at least a portion of at least one of the drive electrode and sense electrode of the electrode pair, wherein the chemical sensing material is responsive to a target analyte.

2. A sensing electrode pair according to claim 1, wherein the substrate comprises an inert material.

3. A sensing electrode pair according to claim 1, further comprising a shield layer disposed on the upper surface of the substrate and underlying the posts elevating the electrodes.

4. A sensing electrode pair according to claim 1, wherein the chemical sensing material is applied as a substantially uniform layer on the drive and sense electrodes.

5. A sensing electrode pair according to claim 1, wherein at least one of the drive electrode and sense electrode is elevated above the substrate by a plurality of posts.

6. A sensing electrode pair according to claim 1, wherein the chemical sensing material is responsive to a plurality of target analytes.

7. A chemical sensor, comprising:

a. a sensing electrode pair according to claim 1;

and

b. circuitry in electrical communication with the electrodes of the sensing electrode pair, wherein the circuitry can detect a change in an electrical parameter of the sensing electrode pair.

8. A chemical sensor according to claim 7 further comprising a power supply for energizing the sensing electrode pair operatively connected thereto.

9. A chemical sensor according to claim 7, wherein the electrical parameter is selected from the group consisting of capacitance, current, resistance, and voltage.

10. A chemical sensor according to claim 7 comprising a plurality sensing electrode pairs, each according to claim 1.

11. A chemical sensor according to claim 10, wherein the chemical sensing material disposed on least one of the sensing electrode pairs differs from the chemical sensing material disposed on another of the sensing electrode pairs.

12. A chemical sensor according to claim 11, wherein the plurality of sensing electrode pairs are arrayed on a microchip that further comprises electrical connections for both the drive electrodes and the sense electrodes of each electrode pair.

13. A method of sensing a target analyte in a fluid, comprising positioning a chemical sensor according to claim 7 in an environment and using the chemical sensor to determine whether the environment contains the target analyte.

14. A method according to claim 13 wherein the fluid is selected from the group consisting of a vapor, a gas, and a liquid.

15. A method according to claim 13 wherein the target analyte is selected from the group consisting of a volatile organic chemical and a biological material.

16. A method according to claim 13 wherein the chemical sensor is configured to detect a plurality of a different target analyte species.

17. A method of making a sensing electrode pair according to claim 1, comprising using microfabrication techniques to build the posts and electrodes.