Method and system for physiologic control of a blood pump

• US 20060241335A1
• Filed: 06/26/2003
• Published: 10/26/2006
• Est. Priority Date: 06/26/2002
• Status: Abandoned Application

• Current Assignee: Gino Morello, Heinrich Schima, Michael Vollkron, Robert J. Benkowski
• Original Assignee: Gino Morello, Heinrich Schima, Michael Vollkron, Robert J. Benkowski
• Inventors: Benkowski, Robert J, Vollkron, Michael, Schima, Heinrich, Morello, Gino
• Application Number:
  US10/560,289
• Publication Number:
  US 20060241335A1
• Time in Patent Office: Days
• US Class Current: 600/16
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/178 drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
• CPC Class Codes: A61M 60/216 including a rotating member acting on the blood, e.g. impeller
• CPC Class Codes: A61M 60/422 the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
• CPC Class Codes: A61M 60/523 using blood flow data, e.g. from blood flow transducers
• CPC Class Codes: A61M 60/546 of blood flow, e.g. by adapting rotor speed
• CPC Class Codes: A61M 60/562 for making blood flow pulsatile in blood pumps that do not intrinsically create pulsatile flow

Abstract

A physiologic control system and method for controlling a blood pump system such as a VAD system. The pump system includes, for example, a blood pump (12) and a controller (80) for controlling the pump. The system may further include a flow measurement device (124). Various control schemes are disclosed, including according controlling the pump to achieve one or more of a desired speed, flow rate, or flow pulsatility. Additionally, various methods for determining maximal flow (the maximum flow that can be achieved for the patient while maintaining certain parameters or within certain boundaries) are disclosed.

Claims

1. A method of controlling a blood pump, comprising:

analyzing an instantaneous flow waveform in both the time domain and frequency domain; and

controlling the pump in response thereto.

6. The method of claim 1, in which the analysis of the flow wave form determines a suction boundary condition.

8. The method of claim 6, further comprising boundary conditions for maximum power, maximum speed, minimum speed, minimum flow, change in flow peak-to-peak amplitude over change in pump speed, change in mean flow over change in pump speed, and change in pump power over change in pump speed.

10. The method of claim 6 or claim 8 where the boundary conditions become control parameters for closed loop control.

11. The method of claim 6 or claim 8 where the boundary conditions cause the control system to clamp pump speed, and where upper boundary conditions do not allow the speed to be increased further while lower boundary conditions do not allow the speed to be decreased further.

12. The method of claim 6 or claim 8 where the boundary condition of suction causes a predetermined decrease in speed then periodically attempts to return to the desired control mode at predetermined intervals.

16. The method of claim 1, 2, 3, 7 or 9 where a fail-safe feature to switch to the Constant Speed mode is automatically enabled in the event of a lost, erroneous, or compromised flow signal.

17. The method of claim 1 where the quality of the flow signal is determined by the frequency domain analysis of the real-time flow waveform.

2. A method of controlling a blood pump, comprising:

analyzing instantaneous and mean values of pump power or pump current;

analyzing pump flow; and

determining a pump speed in response thereto.

3. A method of controlling a blood pump, comprising:

calculating and maintaining a desired flow rate based on an interpolation of a desired flow rate at rest heart rate and a desired flow rate at exercise heart rate.

4. The method of claim 3, where the heart rate is determined from a frequency domain analysis of the flow waveform.

5. The method of claim 3, where the heart rate is determined from a time domain analysis of the flow waveform.

7. A method of controlling a blood pump, the control method having a constant speed, a constant flow, a constant peak-to-peak amplitude, and a maximal control mode.

15. The method of claim 7 where the maximize control mode can be patient enabled via an exercise button.

9. A method of controlling a blood pump which allows selectable levels of unloading with higher levels of unloading presenting a greater risk of running the pump closer to suction.

13. A method of controlling a blood pump which maintains or maximizes the ratio of diastolic flow to mean flow.

14. A method of controlling a blood pump which maintains or maximizes the ratio of peak diastolic flow to mean flow.

18. A method of controlling a blood pump, comprising adapting to a patient'"'"'s individual physiology in response to suction detection events, repeated attempts at achieving a desired dQ/dn or repeated attempts at dW/dn.

19. A method of controlling a blood pump, comprising adapting to a patient'"'"'s individual physiology in response to speed variations, by adapting the desired peak-to-peak flow amplitude to changes of flow and power at repeated variations of speed.