Tissue biopsy and treatment apparatus and method

• US 20060241577A1
• Filed: 01/23/2006
• Published: 10/26/2006
• Est. Priority Date: 03/31/2000
• Status: Abandoned Application

• Current Assignee: AngioDynamics, Inc.
• Original Assignee: Rita Medical Systems Incorporated (AngioDynamics, Inc.)
• Inventors: Balbierz, Daniel J., Johnson, Theodore
• Application Number:
  US11/338,109
• Publication Number:
  US 20060241577A1
• Time in Patent Office: Days
• US Class Current: 606/32
• CPC Class Codes: A61B 10/02 Instruments for taking cell samples or for biopsy A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 18/00 Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body eye surgery A61F9/007; ear surgery A61F11/00
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/1482 having a long rigid shaft for accessing the inner body transcutaneously in minimal invasive surgery, e.g. laparoscopy
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/00022 Sensing or detecting at the treatment site
• CPC Class Codes: A61B 2017/00061 spectrum
• CPC Class Codes: A61B 2017/003 Steerable
• CPC Class Codes: A61B 2017/00849 with respect to tissue, e.g. hollow organs
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/22082 after introduction of a substance
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00083 low, i.e. electrically insulating
• CPC Class Codes: A61B 2018/00142 lubricating
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00654 with individual control of each of a plurality of energy emitting elements
• CPC Class Codes: A61B 2018/0069 using fuzzy logic
• CPC Class Codes: A61B 2018/00702 : Power or energy
• CPC Class Codes: A61B 2018/00791 : Temperature
• CPC Class Codes: A61B 2018/00797 : measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00821 : measured by a thermocouple
• CPC Class Codes: A61B 2018/00827 : Current
• CPC Class Codes: A61B 2018/00875 : Resistance or impedance
• CPC Class Codes: A61B 2018/00892 : Voltage
• CPC Class Codes: A61B 2018/124 : switching the output to different electrodes, e.g. sequentially
• CPC Class Codes: A61B 2018/143 : multiple needles
• CPC Class Codes: A61B 2018/1432 : curved
• CPC Class Codes: A61B 2018/1472 : for use with liquid electrolyte, e.g. virtual electrodes
• CPC Class Codes: A61B 2018/1861 : with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2090/064 : for measuring force, pressure or mechanical tension
• CPC Class Codes: A61B 2090/3782 : transmitter or receiver in catheter or minimal invasive instrument
• CPC Class Codes: A61B 2090/3941 : Photoluminescent markers
• CPC Class Codes: A61B 2090/3966 : Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 2218/002 : Irrigation
• CPC Class Codes: A61B 5/0071 : by measuring fluorescence emission
• CPC Class Codes: A61B 90/39 : Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61N 7/02 : Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: C08L 2201/12 : Shape memory

Abstract

A method of treating a tumor includes providing a tissue biopsy and treatment apparatus that includes an elongated delivery device that has a lumen and is maneuverable in tissue. A sensor array having a plurality of resilient members is deployable from the elongated delivery device. At least one of the plurality of resilient members is positionable in the elongated delivery device in a compacted state and deployable with curvature into tissue from the elongated delivery device in a deployed state. At least one of the plurality of resilient members includes at least one of a sensor, a tissue piercing distal end or a lumen. The sensor array has a geometric configuration adapted to volumetrically sample tissue at a tissue site to differentiate or identify tissue at the tissue site. At least one energy delivery device is coupled to one of the sensor array, at least one of the plurality of resilient members or the elongated delivery device. The apparatus is then introduced into a target tissue site. The sensor array is then utilized to distinguish a tissue type. The tissue type information derived from the sensor array is utilized to position the energy delivery device to ablate a tumor volume. Energy is then delivered from the energy delivery device to ablate or necrose at least a portion of the tumor volume. The sensor array is then utilized to determine an amount of tumor volume ablation.

Claims

1. A method of treating a tumor comprising:

positioning a tissue biopsy and treatment apparatus for detecting and treating a tumor at a selected tissue site,

deploying a sensor array from the appratus, the sensor array including at least one emitting member and at least one detecting member;

deploying a plurality of resilient members from the elongated delivery device, at least one of the plurality of resilient members being positionable in the elongated delivery device in a compacted state and deployable with curvature into tissue from the elongated delivery device in a deployed state, at least one of the plurality of resilient members including at least one sensor,

distinguishing a tissue type utilizing the sensor array to measure a spectral profile of at least one portion of the tissue site to determine a tumor volume;

delivering energy to said resilient members to ablate or necrose at least a portion of the tumor volume; and

determining an amount of tumor volume ablation utilizing the sensor array.

2-104. -104. (canceled)

105. A tissue biopsy and treatment apparatus for detecting and treating tumors, the apparatus comprising:

an elongated delivery device including a lumen, the elongated delivery device being maneuverable in tissue;

at least one sensor array configured to measure a spectral profile of at least a portion of a tissue site, the array comprising at least one emitting member and at least one detecting member;

a plurality of resilient members each having a tissue piercing distal portion, at least one of the plurality of resilient members being positionable in the elongated delivery device in a compacted state and deployable with curvature into tissue from the elongated delivery device in a deployed state, said resilient members being operatively connected to a source of energy for ablating tissue when energy is supplied to the resilient members.

106. The apparatus of claim 105, further comprising:

an optical switching device coupled to the sensor array to switch a mode of at least one of the emitting members or the detecting members.

107. The apparatus of claim 105, wherein the sensor array is deployable from the elongated delivery device.

108. The apparatus of claim 105, wherein at least one of the sensor arrays is positioned in one of the resilient members.

109. The apparatus of claim 108, wherein the sensor array is fixedly positioned in the resilient member.

110. The apparatus of claim 108, wherein the sensor array is deployable from the resilient member.

111. The apparatus of claim 105, further comprising:

an optical measurement device operatively connected to the at least one sensor array.

112. The apparatus of claim 105, further comprising:

a light source operatively connected to the at least one sensor array.

113. The apparatus of claim 105, further comprising:

at least one advancement device operatively connected to at least one of the sensor array and the plurality of resilient members.

114. The apparatus of claim 105, further comprising:

at least one thermal sensor positioned on at least one of (i) the sensor array, (ii) the plurality of resilient members, and (iii) the elongated delivery device.