Treatment of movement disorders by extra dural motor cortex stimulation
2 Assignments
0 Petitions
Accused Products
Abstract
System and methods for introducing one or more stimulating drugs and/or applying electrical stimulation to the cortex of the brain to treat movement disorders uses at least one implantable system control unit (SCU), specifically an implantable signal/pulse generator (IPG) or microstimulator with two or more electrodes in the case of electrical stimulation, and an implantable pump with one or more infusion outlets in the case of drug infusion. In certain embodiments, a single SCU provides both electrical stimulation and one or more stimulating drugs. In some embodiments, one or more sensed conditions are used to adjust stimulation parameters.
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Citations
39 Claims
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1-2. -2. (canceled)
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3. A method of treating a Patient with a movement disorder, comprising:
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implanting in the patient'"'"'s head at least one leadless system control unit for controlling delivery of at least one stimulus comprising an electrical stimulation current and one or more drugs, said system control unit being connected to at least one infusion outlet and having an outer casing and a number of electrodes disposed on the casing;
applying the electrical stimulation current via said electrodes to at least one area of the brain affecting a movement disorder in order to at least in part alleviate the movement disorder of the patient being treated;
delivering the one or more drugs through the at least one outlet to the at least one area of the brain affecting the movement disorder; and
selecting the at least one area of the brain from at least one of a motor cortex, a premotor cortex, and a sensory vortex. - View Dependent Claims (5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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4. (canceled)
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21. A method of treating a patient with a movement disorder, comprising:
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implanting in the patient'"'"'s head at least one leadless system control unit for controlling delivery of at least one stimulus comprising an electrical stimulation current, said system control unit having an outer casing and a number of electrodes disposed on the casing;
applying the at least one stimulus via said electrodes to at least one area of the brain affecting a movement disorder in order to at least in part alleviate the movement disorder of the patient being treated;
selecting the at least one area of the brain from at least one of a motor cortex, a premotor cortex, and a sensory cortex; and
applying at least one inhibitory stimulus to the at least one selected area of the brain, thereby decreasing activity of the at least one selected area. - View Dependent Claims (23, 24, 25, 26, 28, 29, 30, 31, 32, 33, 34, 35)
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22. (canceled)
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27. (canceled)
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36. (canceled)
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37. A system for treating a patient with a movement disorder, said system comprising:
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a leadless system control unit having an outer casing and a number of electrodes built into the casing; and
at least one infusion outlet coupled to said system control unit;
wherein said system control unit is configured to deliver an electrical stimulation current via said electrodes and one or more drugs via said at least one infusion outlet to an area within the brain of a patient in accordance with one or more stimulation parameters configured to treat said movement disorder; and
wherein said system control unit is further configured to be implanted within a head of said patient so as to deliver said electrical stimulation current and said one or more drugs to said area within said brain which comprises at least one or more of a motor cortex, premotor cortex, and sensory cortex. - View Dependent Claims (38, 39)
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Specification