Hydrophilized membrane and process for hydrophilization thereof
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Abstract
The present invention relates to a hydrophilized membrane which has greatly suppressed adhesion of blood cells such as erythrocytes, leukocytes and blood platelets within blood, by easily conducting hydrophilization of a hydrophobic porous membrane, and a process for the hydrophilization. The present invention relates to a hydrophilized hydrophobic porous membrane which is obtained by impregnating a medical supply of which the part which comes into contact with blood is hydrophobic in a solution of a substance having surface activity, then rinsing in a solvent into which the surfactant is soluble, and adsorbing an extremely small amount of the substance having surface activity to the surface of the part which comes into contact with blood, wherein the adhesion of blood cells such as erythrocytes, leukocytes and blood platelets within blood is greatly suppressed. The present invention also relates to a process for hydrophilization.
18 Citations
34 Claims
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1-20. -20. (canceled)
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21. A process for suppressing blood cell adhesion by using a hydrophilized porous membrane for medical use, wherein the hydrophilized porous membrane comprises:
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a hydrophobic porous membrane, and a substance having surface activity, said substance being adsorbed on a surface of the hydrophobic porous membrane in an amount of 0.02 mg to 250 mg per dry weight (g) of said membrane, and the substance having surface activity is at least one member selected from the group consisting of purified vitelline lecithin, highly purified vitelline lecithin, purified soybean lecithin and hydrogenated polyoxyethylene castor oil. - View Dependent Claims (22, 23)
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24. A process for suppressing blood cell adhesion by using medical equipment having a hydrophobic surface, wherein the medical equipment comprises:
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a hydrophobic part to be in contact with blood and a substance having surface activity, and said substance having surface activity is adsorbed on said hydrophobic surface in an amount of 0.02 mg to 250 mg based on unit dry weight (g). - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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Specification