Modified growth hormones
First Claim
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1. A modified growth hormone polypeptide, comprising an amino acid replacement of Y for 1 in an unmodified growth hormone polypeptide at a locus corresponding to amino acid Y42 of a mature growth hormone polypeptide set forth in SEQ ID NO:
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Abstract
Provided are modified growth hormone polypeptides, nucleic acid molecules encoding modified growth hormone polypeptides and methods of generating modified growth hormone polypeptides. Also provided are methods of treatment using modified growth hormone polypeptides.
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16 Claims
- 1. A modified growth hormone polypeptide, comprising an amino acid replacement of Y for 1 in an unmodified growth hormone polypeptide at a locus corresponding to amino acid Y42 of a mature growth hormone polypeptide set forth in SEQ ID NO:
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