Method and apparatus for detection of tachyarrhythmia using cycle lengths

• US 20060247548A1
• Filed: 12/29/2005
• Published: 11/02/2006
• Est. Priority Date: 04/29/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Sarkar, Shantanu, Ritscher, David E.
• Granted Patent: US 7,537,569 B2
• Time in Patent Office: Days
• US Class Current: 600/515
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia

Abstract

A multi-layer method for detecting atrial arrhythmias using ventricular cycle length information that includes performing a base layer algorithm for detecting the onset and offset of an atrial tachyarrhythmia. The multi-layer method further includes one or more higher layer algorithms executed in response to a base layer detection to confirm or reject the base layer detection. The base layer is designed to operate with high sensitivity to atrial fibrillation and/or organized atrial tachycardia and the higher layer is designed to operate with high sensitivity and high specificity to atrial fibrillation and/or organized atrial tachycardia.

Claims

1. A method of identifying a cardiac event, comprising:

detecting sensed events using a first detection format in a first state during detection of other than the cardiac event;

advancing from the first state to a second state corresponding to suspending the detecting using the first detection format and detecting sensed events using a second format different from the first detection format in response to the first detection format determining the sensed events correspond to the cardiac event while in the first state;

advancing from the second state to the first state in response to the second detection format determining the sensed events do not correspond to the cardiac event while in the second state;

advancing from the second state to a third state in response to the second detection format determining the sensed events correspond to the cardiac event while in the second state, the third state corresponding to detecting sensed events using the first detection format;

advancing from the third state to a fourth state in response to the sensed events being determined not to correspond to the cardiac event while in the third state, the fourth state corresponding to suspending the detection using the first format and detecting sensed events using the second detection format;

advancing from the fourth state to the third state in response to the sensed events being determined to correspond to the cardiac event while in the fourth state; and

advancing from the fourth state to the first state in response to the sensed events being determined not to correspond to the cardiac event while in the fourth state.

5. The method of claim 1, wherein the detecting using the second detection format is performed within a predetermined time period, the method further comprising advancing from the second state to one of the first state and the third state and from the fourth state to one of the third state and the first state within the predetermined time period.

6. The method of claim 5, wherein the predetermined time period corresponds to a predetermined number of detected RR-intervals.

7. The method of claim 1, wherein the second detection format comprises:

determining a plurality of cycle lengths associated with sensed cardiac signals;

determining differences between consecutive cycle lengths of the determined plurality of cycle lengths;

determining cluster signature metrics in response to the determined differences;

generating a plot corresponding to the determined differences; and

determining a number of the determined differences that are located within a plurality of segments of the plot defined by a range of magnitudes and phases relative to an origin of the plot and corresponding to patterns associated with the cardiac event.

8. The method of claim 1, wherein the first detection format includes a first metric corresponding to a first change in cycle lengths, a second metric corresponding to one of a decrease in ventricular rate and an increase in ventricular rate, and a third metric corresponding to a second change in cycle lengths.

9. The method of claim 8, wherein the cardiac event is determined to correspond to onset of atrial fibrillation in response to one of the first metric and the second metric, and to onset of organized atrial tachycardia in response to one of the first metric, the second metric and the third metric.

10. The method of claim 8, wherein the cardiac event is determined to correspond to onset of atrial fibrillation in response to one of the first metric and the second metric, and to onset of organized atrial tachycardia in response to one of the first and the third metric and the second metric.

2. The method of claim 2, further comprising detecting sensed events using the first detection format and the second detection format while in the third state.

4. The method of claim 3, further comprising alternating between detecting sensed events using the first detection format and detecting sensed events using the second detection format while in the third state.

11. A method of identifying a cardiac event, comprising:

detecting sensed events using a first detection format in a first state during detection of other than the cardiac event;

advancing from the first state to a second state corresponding to suspending the detecting using the first detection format and detecting sensed events using a second format different from the first detection format in response to the first detection format determining the sensed events correspond to the cardiac event while in the first state;

advancing from the second state to the first state in response to the second detection format determining the sensed events do not correspond to the cardiac event while in the second state;

advancing from the second state to a third state in response to the second detection format determining the sensed events correspond to the cardiac event while in the second state, the third state corresponding to detecting sensed events using the first detection format;

advancing from the third state to a fourth state in response to the sensed events being determined not to correspond to the cardiac event while in the third state, the fourth state corresponding to suspending the detection using the first format and detecting sensed events using the second detection format;

advancing from the fourth state to the third state in response to the sensed events being determined to correspond to the cardiac event while in the fourth state; and

advancing from the fourth state to the first state in response to the sensed events being determined not to correspond to the cardiac event while in the fourth state, wherein the second detection format comprises;

determining a plurality of cycle lengths associated with sensed cardiac signals;

determining differences between consecutive cycle lengths of the determined plurality of cycle lengths;

determining cluster signature metrics in response to the determined differences;

generating a plot corresponding to the determined differences; and

determining a number of the determined differences that are located within a plurality of segments of the plot defined by a range of magnitudes and phases relative to an origin of the plot and corresponding to patterns associated with the cardiac event, and wherein the first detection format includes a first metric corresponding to a first change in cycle lengths, a second metric corresponding to one of a decrease in ventricular rate and an increase in ventricular rate, and a third metric corresponding to a second change in cycle lengths.

12. The method of claim 11, further comprising detecting sensed events using the first detection format and the second detection format while in the third state.

13. The method of claim 12, further comprising alternating between detecting sensed events using the first detection format and detecting sensed events using the second detection format while in the third state.

14. The method of claim 12, wherein the detecting using the second detection format is performed within a predetermined time period, the method further comprising advancing from the second state to one of the first state and the third state and from the fourth state to one of the third state and the first state within the predetermined time period.

15. The method of claim 14, wherein the predetermined time period corresponds to a predetermined number of detected RR-intervals.

16. The method of claim 11 wherein the cardiac event is determined to correspond to onset of atrial fibrillation in response to one of the first metric and the second metric, and to onset of organized atrial tachycardia in response to one of the first metric, the second metric and the third metric.

17. The method of claim 11, wherein the cardiac event is determined to correspond to onset of atrial fibrillation in response to one of the first metric and the second metric, and to onset of organized atrial tachycardia in response to one of the first and the third metric and the second metric.

18. A method for detecting atrial arrhythmias, comprising:

executing a base layer algorithm for detecting an onset of an atrial tachyarrhythmia;

executing a higher layer algorithm in response to detecting the onset of the atrial tachyarrhythmia by the base layer algorithm for confirming or rejecting the atrial tachyarrhythmia onset detection by the base layer;

executing the base layer algorithm in response to confirmation of the atrial tachyarrhythmia detection by the higher layer algorithm for detecting an offset of the atrial tachyarrhythmia and otherwise executing the base layer algorithm in response to rejection of the atrial tachyarrhythmia by the higher layer algorithm for detecting an onset of an atrial tachyarrhythmia;

executing the higher layer algorithm in response to detecting the offset of the atrial tachyarrhythmia by the base layer algorithm for confirming the termination of the atrial tachyarrhythmia.