Local delivery of an active agent from an orthopedic implant
First Claim
1. A posterior spinal fixation device or dynamic spinal stabilization device comprising an active agent-delivery component, wherein said active agent-delivery component has an active agent impregnated therein or adsorbed thereon or otherwise contained therein and is configured to release the active agent locally after the device is implanted in a patient.
2 Assignments
0 Petitions
Accused Products
Abstract
A posterior spinal fixation device or dynamic spinal stabilization device or other orthopedic device includes an active agent-delivery component. The active agent-delivery component has an active agent impregnated therein or adsorbed thereon or otherwise contained therein and is configured to release the active agent locally after the device is implanted in a patient. One preferred type of implant in accordance with the invention is an implant for stabilizing a spinal motion segment that includes a spacer member positionable between adjacent spinous processes or transverse processes or other posterior spinal element, including an implanted anchor element.
391 Citations
41 Claims
- 1. A posterior spinal fixation device or dynamic spinal stabilization device comprising an active agent-delivery component, wherein said active agent-delivery component has an active agent impregnated therein or adsorbed thereon or otherwise contained therein and is configured to release the active agent locally after the device is implanted in a patient.
- 20. An orthopedic implant device comprising an active agent-delivery component, wherein said active agent-delivery component comprises an elastic material having said active agent absorbed therein or adsorbed thereon, wherein said device is configured to release said active agent locally after said device is implanted in a patient, and wherein said device is configured such that a dose of said active agent is caused to be released or released at an increased rate by (a) compressing said active agent-delivery component, (b) stretching said component, or (c) by applying a torque to said component.
-
38. An orthopedic implant device comprising a bone stabilization member positionable along adjacent bone portions outside an interspace between the bone portions, and an active agent-delivery component, wherein said device is configured to release said active agent locally after said device is implanted in a patient.
-
39. A method for delivering an active agent to a patient at a location adjacent an orthopedic implant device, comprising:
-
providing an orthopedic implant device comprising an active agent-delivery component, wherein the active agent-delivery component has an active agent impregnated therein or adsorbed thereon or otherwise contained therein and is configured to release the active agent locally after the device is implanted in a patient; and
surgically implanting the device in a posterior spinal location. - View Dependent Claims (40, 41)
-
Specification