System and method for detecting hypoglycemia based on a paced depolarization integral using an implantable medical device
First Claim
1. A method for use with an implantable medical device for detecting hypoglycemia in a patient in which the device is implanted, the method comprising:
- detecting a parameter representative of the energy associated with electrical cardiac signals corresponding to ventricular evoked responses; and
detecting an episode of hypoglycemia based on the parameter.
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Accused Products
Abstract
Techniques are provided for use with an implantable medical device such as a pacemaker or implantable cardioverter/defibrillator (ICD) for predicting and detecting hypoglycemia. In one example, the device tracks changes in a paced depolarization integral (PDI). A significant increase in PDI over a relatively short period of time indicates the onset of hypoglycemia (this can also be confirmed with QT changes). Upon detection of hypoglycemia, appropriate warning signals are generated to alert the patient. Certain therapies automatically provided by the implantable device may also be controlled in response to hypoglycemia. For example, if the patient is an insulin-dependent diabetic and the implantable device is equipped with an insulin pump capable of delivering insulin directly into the bloodstream, insulin delivery is automatically suspended until blood glucose levels return to acceptable levels. If the device is an ICD, it may be controlled to begin charging defibrillation capacitors upon detection of hypoglycemia so as to permit prompt delivery of a defibrillation shock, which may be needed if hypoglycemia triggers ventricular fibrillation. The detection techniques may be used in conjunction with other hypoglycemia detection techniques to improve detection specificity.
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Citations
19 Claims
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1. A method for use with an implantable medical device for detecting hypoglycemia in a patient in which the device is implanted, the method comprising:
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detecting a parameter representative of the energy associated with electrical cardiac signals corresponding to ventricular evoked responses; and
detecting an episode of hypoglycemia based on the parameter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A system for use with an implantable medical device for detecting hypoglycemia in a patient in which the device is implanted comprising:
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sensing circuitry operative to sense electrical cardiac signals corresponding to ventricular evoked responses with the patient;
a paced depolarization integral (PDI) calculator operative to calculate a parameter representative of the energy associated with the electrical cardiac signals corresponding to the ventricular evoked responses; and
a hypoglycemia detection system operative to detect an episode of hypoglycemia based the parameter. - View Dependent Claims (18)
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19. A system for use with an implantable medical device for detecting hypoglycemia in a patient in which the device is implanted comprising:
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means for detecting a parameter representative of the energy associated with the electrical cardiac signals corresponding to ventricular evoked responses within the patient; and
means for detecting an episode of hypoglycemia based the changes in the parameter.
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Specification