Implant

• US 20060247781A1
• Filed: 04/29/2005
• Published: 11/02/2006
• Est. Priority Date: 04/29/2005
• Status: Abandoned Application

• Current Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Original Assignee: SDGI Holdings Incorporated (Medtronic Plc)
• Inventors: Francis, Tom J.
• Application Number:
  US11/117,485
• Publication Number:
  US 20060247781A1
• Time in Patent Office: Days
• US Class Current: 623/17.160
• CPC Class Codes: A61F 2/442 Intervertebral or spinal discs, e.g. resilient non-disc-shaped intervertebral inflatable pockets A61F2/441; non-disc-shaped intervertebral fusion implants A61F2/4455
• CPC Class Codes: A61F 2/4611 of spinal prostheses
• CPC Class Codes: A61F 2002/2817 Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/3008 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2002/30092 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2002/30594 slotted, e.g. radial or meridian slot ending in a polar aperture, non-polar slots, horizontal or arcuate slots
• CPC Class Codes: A61F 2002/30677 Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
• CPC Class Codes: A61F 2002/30919 Sleeves
• CPC Class Codes: A61F 2002/4415 elements of the prosthesis being arranged in a chain like manner
• CPC Class Codes: A61F 2002/444 for replacing the nucleus pulposus
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers

Abstract

An intervertebral disc nucleus replacement is provided that is configurable into a first configuration to be assumed while the replacement is implanted in the nuclear cavity and a second configuration to be assumed during the procedure of inserting the replacement into the nuclear cavity. The first configuration may have an accordion-like structure formed by a plurality of sections folded in an alternating, zigzag-like manner, and may be sized and shaped to conform to the nuclear cavity. The second configuration may be formed by straightening the plurality of folded sections into an unfolded, elongated, linear member, thereby affording a smaller effective cross-section. The nucleus replacement may be made of an elastic material having shape memory and may be formed so that the first configuration is an unmanipulated or relaxed configuration and the second configuration is a manipulated or unrelaxed configuration.

Claims

1. An intervertebral disc nucleus pulposus implant, comprising:

a member for insertion, through an opening in an intervertebral disc annulus fibrosis, into an intervertebral disc space, said member being configurable into a first, predetermined configuration in which said member is folded at at least three positions, and a second configuration in which said member is not folded at at least one of the three positions, the second configuration being for the insertion of said member, said member being configurable back into the first configuration after the insertion.

2. An intervertebral disc nucleus pulposus implant according to claim 1,

wherein, in the first configuration, said member comprises a plurality of substantially elongate sections with a plurality of spaces provided therebetween, respectively, the plurality of substantially elongate sections including two end sections and at least one central section, each of the substantially elongate sections having a distal end and a proximal end, each central section being connected, at a proximal end thereof, to a proximal end of an adjacent section, and, at a distal end thereof, to a distal end of another adjacent section, whereby the sections are connected in a zigzag-like fashion, and

wherein, in the second configuration, said member is more linear than in the first configuration.

3. An intervertebral disc nucleus pulposus implant according to claim 1, wherein said member is formed of an elastic material that has shape memory, and wherein the first configuration is a relaxed configuration and the second configuration is an unrelaxed configuration.

4. An intervertebral disc nucleus pulposus implant, comprising:

a member for insertion, through an opening in an intervertebral disc annulus fibrosis, into an intervertebral disc space, said member being configurable into a first, unmanipulated configuration in which said member is folded at at least a first position and said member is reverse folded at at least a second position, and a second configuration in which said member is not folded at at least one of the first and second positions, the second configuration being for the insertion of said member, said member being configurable back into the first configuration after the insertion.

5. An intervertebral disc nucleus pulposus implant according to claim 4,

wherein, in the first configuration, said member comprises a plurality of substantially elongate sections with a plurality of spaces provided therebetween, respectively, the plurality of substantially elongate sections including two end sections and at least one central section, each of the substantially elongate sections having a distal end and a proximal end, each central section being connected, at a proximal end thereof, to a proximal end of an adjacent section, and, at a distal end thereof, to a distal end of another adjacent section, whereby the sections are connected in a zigzag-like fashion, and

wherein, in the second configuration, said member is more linear than in the first configuration.

6. An intervertebral disc nucleus pulposus implant according to claim 4, wherein, after insertion into the intervertebral disc space, said member is to assume the first configuration and to retain the first configuration while implanted in the intervertebral disc space.

7. An intervertebral disc nucleus pulposus implant according to claim 4, wherein said member is formed of an elastic material that has shape memory, and wherein the first configuration is a relaxed configuration and the second configuration is an unrelaxed configuration.

8. An intervertebral disc nucleus pulposus implant according to claim 4, wherein, when said member is fully unfolded, said member forms an unbranched, elongate member symmetric about a single longitudinal axis.

9. An intervertebral disc nucleus pulposus implant according to claim 4, wherein said member is for insertion into a space of the nucleus pulposus, so as to be able to be movably in contact with the annulus fibrosis and with two adjacent vertebral end plates, above and below the space of the nucleus pulposus, respectively.

10. An intervertebral disc nucleus pulposus implant according to claim 4, wherein, when said member is in the first configuration, said member has opposite convex surfaces, for conforming to a natural concavity of two adjacent vertebral end plates, which are disposed above and below said member when said member is implanted in the intervertebral disc space.

11. An intervertebral disc nucleus pulposus implant according to claim 4, wherein said member is capable of maintaining a natural spacing between two adjacent vertebrae.

12. An intervertebral disc nucleus pulposus implant according to claim 4, wherein, when said member is in the second configuration, said member has a cross-section, taken perpendicular to a longitudinal axis of said member, that has a width less than or equal to approximately 1.5 mm.

13. An intervertebral disc nucleus pulposus implant according to claim 4, wherein, when said member is in the second configuration, a cross-section of said member, taken perpendicular to a longitudinal axis of said member, has a substantially polygonal shape without voids therein, and has a perimeter that is at least substantially smoothly continuous.

14. An intervertebral disc nucleus pulposus implant according to claim 4, wherein the first configuration has a length and a width, and the second configuration has a cross-section, taken perpendicular to a longitudinal axis of said member, the cross-section having a length and a width, and

wherein the ratio of the width of the cross-section of said member in the second configuration to the length of said member in the first configuration is less than or equal to approximately 0.25.

15. An intervertebral disc nucleus pulposus implant according to claim 4, wherein said member is formed of a thermoplastic elastomer.

16. An implant, comprising:

a member for insertion through an opening, said member being configurable into a first, unmanipulated configuration having a length and a width, and a second configuration having a cross-section, taken perpendicular to a longitudinal axis of said member, the cross-section having a length and a width, the second configuration being for the insertion of said member, said member being configurable back into the first configuration after the insertion,

wherein, when said member is in the first configuration, said member comprises at least three sections extending transverse to the length of said member in the first configuration, and

wherein the ratio of the width of the cross-section of said member in the second configuration to the length of said member in the first configuration is less than or equal to approximately 0.25.

17. An implant according to claim 16,

wherein said at least three sections are substantially elongate sections with a plurality of spaces provided therebetween, respectively, the substantially elongate sections including two end sections and at least one central section, each of the substantially elongate sections having a distal end and a proximal end, each central section being connected, at a proximal end thereof, to a proximal end of an adjacent section, and, at a distal end thereof, to a distal end of another adjacent section, whereby the sections are connected in a zigzag-like fashion, and

wherein, in the second configuration, said member is more linear than in the first configuration.

18. An implant according to claim 16, wherein said member is formed of an elastic material that has shape memory, and wherein the first configuration is a relaxed configuration and the second configuration is an unrelaxed configuration.

19. An implant according to claim 16, wherein, when said member is fully unfolded, said member forms an unbranched, elongate member symmetric about a single longitudinal axis.

20. An implant according to claim 16, wherein, when said member is in the second configuration, the width of the cross-section is less than or equal to approximately 1.5 mm.

21. An implant according to claim 16, wherein the ratio of the width of the cross-section of said member in the second configuration to the length of said member in the first configuration is less than or equal to approximately 0.15.

22. An implant according to claim 16, wherein the implant is an intervertebral disc nucleus pulposus implant, for insertion, through an opening in an intervertebral disc annulus fibrosis, into an intervertebral disc space.