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Method of treating multiple myeloma using 17-AAG or 17-AG or a prodrug of either in combination with a proteasome inhibitor

  • US 20060252740A1
  • Filed: 04/26/2006
  • Published: 11/09/2006
  • Est. Priority Date: 04/29/2005
  • Status: Abandoned Application
First Claim
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1. A method of treating multiple myeloma (MM) in a subject in need of such treatment, comprising the step of administering to said subject a therapeutically effective dose of 17-allylamino-17-demethoxy-geldanamycin (17-AAG) or 17-aminogeldanamycin (17-AG) or a prodrug of either 17-AAG or 17-AG, and a therapeutically effective dose of a proteasome inhibitor, and optionally repeating said step until no further therapeutic benefit is obtained.

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