Augmentation of extinction via administration of sub-antimicrobial doses of D-cycloserine
First Claim
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1. A method for facilitating extinction of a deleterious, high-anxiety response in a subject, comprising:
- (A) administering to said subject a sub-antimicrobial dose of D-cycloserine; and
(B) exposing said subject to an extinction learning event within eight hours of said administering of said sub-antimicrobial dose of D-cycloserine.
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Abstract
Methods are provided for facilitating psychological extinction of a deleterious, high-anxiety response that is disproportionate to the threat offered by a given stimulus. An afflicted subject is treated with a sub-antimicrobial dose of D-cycloserine in conjunction with extinction training. The methods are relevant for treatment of anxiety disorders, including phobic disorders and PTSD, in addition to other afflictions such as insomnia and erectile dysfunction.
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24 Claims
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1. A method for facilitating extinction of a deleterious, high-anxiety response in a subject, comprising:
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(A) administering to said subject a sub-antimicrobial dose of D-cycloserine; and
(B) exposing said subject to an extinction learning event within eight hours of said administering of said sub-antimicrobial dose of D-cycloserine. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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Specification