Stratum corneum piercing device

• US 20060253079A1
• Filed: 04/25/2005
• Published: 11/09/2006
• Est. Priority Date: 04/25/2005
• Status: Abandoned Application

• Current Assignee: Johnson & Johnson Consumer Companies Incorporated (Johnson & Johnson)
• Original Assignee: Johnson & Johnson Consumer Companies Incorporated (Johnson & Johnson)
• Inventors: Sun, Ying, McDonough, Justin, Wu, Jeffrey M., Liu, Jue-Chen, Maghribi, Mariam, Lambino, Danilo
• Application Number:
  US11/113,952
• Publication Number:
  US 20060253079A1
• Time in Patent Office: Days
• US Class Current: 604/173
• CPC Class Codes: A61B 2017/00765 Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 2037/0046 Solid microneedles
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61N 1/306 Arrangements where at least part of the apparatus is introduced into the body
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428
• CPC Class Codes: A61P 17/10 Anti-acne agents

Abstract

The present invention features a stratum corneum-piercing device including a microprotrusion member having a skin-contacting surface and plurality of stratum corneum piercing microprotrusions thereon, the device being adapted to move the microprotrusion member lateral to the surface of the skin surface upon contact with the skin.

Claims

1. A stratum corneum-piercing device comprising a microprotrusion member having a skin-contacting surface and plurality of stratum corneum piercing microprotrusions thereon, said device being adapted to rotate said microprotrusion member lateral to the surface of the skin surface upon contact with said skin.

3. A device of claim 1, wherein said device comprises an inner housing and an outer housing, wherein said microprotrusion member is attached to said inner housing, said inner housing is adapted to move into said outer housing and rotate upon contact with the skin.

4. A device of claim 1, wherein said device comprises an inner housing and an outer housing, wherein said microprotrusion member is attached to said outer housing, said inner housing is adapted to move into said outer housing and rotate said outer housing upon contact with the skin.

5. A device of claim 1, wherein said device comprises from about 5 to about 100 microprotrusions having a length of from about 100 to about 500 microns.

6. A device of claim 1, wherein said device comprises from about 5 to about 100 microprotrusions having a length of from about 100 to about 500 microns.

7. A device of claim 1, wherein said device is further adapted to apply a composition to said skin upon contact with said skin.

8. A device of claim 1, wherein said device is further adapted to apply a composition to said skin upon contact with said skin during said movement of said microprotrusion member.

9. A device of claim 7, wherein said device comprises a reservoir comprising said composition and said skin-contacting surface has at least one opening, wherein said device is adapted to move said composition from said reservoir, through said at least one opening, and onto said skin-contacting surface.

10. A device of claim 7, wherein said device comprises a composition reservoir containing said composition, wherein at least one of said microprotrusions is hollow, and said composition reservoir is in communication with said at least one hollow microprotrusion such that said device is adapted to composition can move from said composition reservoir and through said at least one hollow microprotrusion.

11. A device of claim 8, wherein said device comprises a reservoir comprising said composition and said skin-contacting surface has at least one opening, wherein said device is adapted to move said composition from said reservoir, through said at least one opening, and onto said skin-contacting surface.

12. A device of claim 8, wherein said device comprises a composition reservoir containing said composition, wherein at least one of said microprotrusions is hollow, and said composition reservoir is in communication with said at least one hollow microprotrusion such that said device is adapted to composition can move from said composition reservoir and through said at least one hollow microprotrusion.

13. A device of claim 1, wherein said device is adapted to remove bodily fluids from the skin upon contact with said skin.

14. A device of claim 13, wherein said device comprises a collection reservoir for containing fluids removed from skin.

15. A device of claim 14, wherein said collection reservoir comprises an absorbent material affixed to at least a portion of said skin-contacting surface.

16. A device of claim 13, wherein said skin-contacting surface has at least one openings, and said collection reservoir is in communication with said at least one opening such that said fluids can move from said skin, through said at least one opening, and into said collection reservoir.

17. A device of claim 13, wherein at least one of said microprotrusions is hollow, and said collection reservoir is in communication with said at least one hollow microprotrusion such that said fluids can move from said skin, through said at least one hollow microprotrusion, and into said collection reservoir.

18. A device of claim 1, wherein said device comprises a composition containing an active agent coated on (i) at least a portion of said skin-contacting surface, (ii) at least a portion of one or more of said stratum-corneum piercing microprotrusions, or (iii) at least a portion of said skin-contacting surface and at least a portion of one or more of said stratum-corneum piercing microprotrusions.

19. A device of claim 1, wherein said device comprises a composition containing an active agent coated on (i) at least a portion of said skin-contacting surface, (ii) at least a portion of one or more of said stratum-corneum piercing microprotrusions, or (iii) at least a portion of said skin-contacting surface and at least a portion of one or more of said stratum-corneum piercing microprotrusions.

20. A device of claim 1, wherein said device is adapted to rotate said microprotrusion member from about 45 to about 135 degrees.

2. (canceled)