Controlled delivery of intermittent stress augmentation pacing for cardioprotective effect
First Claim
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1. A cardiac rhythm management device, comprising:
- a pacing channel for delivering pacing pulses to a selected ventricular myocardial site;
a controller for controlling the delivery of pacing pulses in accordance with a programmed pacing mode;
wherein the controller is programmed to switch from a normal operating mode to a stress augmentation mode in which a particular region or regions of the ventricular myocardium are subjected to increased mechanical stress as compared with the stress experienced by those regions during the normal operating mode; and
, wherein the controller is programmed to switch to the stress augmentation mode for a specified time period upon expiration of a timer, where the timer is defined with an expiration which coincides with when the patient is expected to awaken from sleep.
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Abstract
A device and method for delivering electrical stimulation to the heart in a manner which provides a protective effect against subsequent ischemia is disclosed. The protective effect is produced by configuring a cardiac pacing device to intermittently switch from a normal operating mode to a stress augmentation mode in which the spatial pattern of depolarization is varied to thereby subject a particular region or regions of the ventricular myocardium to increased mechanical stress.
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19 Claims
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1. A cardiac rhythm management device, comprising:
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a pacing channel for delivering pacing pulses to a selected ventricular myocardial site;
a controller for controlling the delivery of pacing pulses in accordance with a programmed pacing mode;
wherein the controller is programmed to switch from a normal operating mode to a stress augmentation mode in which a particular region or regions of the ventricular myocardium are subjected to increased mechanical stress as compared with the stress experienced by those regions during the normal operating mode; and
,wherein the controller is programmed to switch to the stress augmentation mode for a specified time period upon expiration of a timer, where the timer is defined with an expiration which coincides with when the patient is expected to awaken from sleep. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A cardiac rhythm management device, comprising:
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a pacing channel for delivering pacing pulses to a selected ventricular myocardial site;
a controller for controlling the delivery of pacing pulses in accordance with a programmed pacing mode;
a posture sensor interfaced to the controller;
wherein the controller is programmed to switch from a normal operating mode to a stress augmentation mode in which a particular region or regions of the ventricular myocardium are subjected to increased mechanical stress as compared with the stress experienced by those regions during the normal operating mode; and
,wherein the controller is programmed to switch to the stress augmentation mode for a specified time period upon receiving a signal from the posture sensor indicating that the patient'"'"'s posture has changed from a supine position to an erect or sitting position. - View Dependent Claims (8, 9, 10, 11, 12, 13)
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14. A cardiac rhythm management device, comprising:
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a pacing channel for delivering pacing pulses to a selected ventricular myocardial site;
a sensing channel for detecting intrinsic cardiac activity;
a controller for controlling the delivery of pacing pulses in accordance with a programmed pacing mode;
wherein the controller is programmed to determine an LF/HF ratio by analyzing data received from the sensing channel;
wherein the controller is programmed to switch from a normal operating mode to a stress augmentation mode in which a particular region or regions of the ventricular myocardium are subjected to increased mechanical stress as compared with the stress experienced by those regions during the normal operating mode; and
,wherein the controller is programmed to switch to the stress augmentation mode for a specified time period when the LF/HF ratio is above a specified threshold value. - View Dependent Claims (15, 16, 17, 18, 19)
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Specification