Devices and methods for detecting and treating inadequate tissue perfusion
First Claim
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1. A medical method for detecting and treating inadequate tissue perfusion of a patient, comprising:
- providing a sensor for measuring an intravascular blood parameter;
positioning the sensor on a portion of the patient'"'"'s vasculature;
measuring the intravascular parameter using the sensor;
detecting inadequate tissue perfusion based on the intravascular parameter measured by the sensor;
delivering a stimulus to increase tissue perfusion as a function of the measured intravascular parameter.
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Abstract
Devices and methods for detecting inadequate tissue perfusion by measuring a parameter other than heart rate such as vascular blood pressure, intracardiac blood pressure, vascular blood flow or tissue perfusion, in addition to or as a substitute for heart rate. Such devices and methods improve the accuracy of determining when and to what degree therapy should be administered to treat inadequate tissue perfusion, such as pre-syncope, syncope, or orthostatic hypotension, particularly in the absence of abnormal cardiac function.
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Citations
36 Claims
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1. A medical method for detecting and treating inadequate tissue perfusion of a patient, comprising:
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providing a sensor for measuring an intravascular blood parameter;
positioning the sensor on a portion of the patient'"'"'s vasculature;
measuring the intravascular parameter using the sensor;
detecting inadequate tissue perfusion based on the intravascular parameter measured by the sensor;
delivering a stimulus to increase tissue perfusion as a function of the measured intravascular parameter. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A medical method for detecting and treating inadequate tissue perfusion of a patient, comprising:
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providing a sensor for measuring intracardiac pressure;
positioning the sensor in or on the patient'"'"'s heart;
measuring intracardiac pressure of the left side of the patient'"'"'s heart using the sensor;
detecting inadequate tissue perfusion based on the intracardiac pressure measurement;
delivering a stimulus to increase tissue perfusion as a function of the intracardiac pressure measurement. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14)
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15. A medical method for detecting and treating inadequate tissue perfusion of a patient, comprising:
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providing a sensor for measuring tissue perfusion;
providing a therapeutic device for delivering a stimulus to increase tissue perfusion;
positioning the sensor in the patient remote from the therapeutic device;
measuring tissue perfusion using the sensor;
detecting inadequate tissue perfusion based on the tissue perfusion measurement; and
delivering a stimulus to increase tissue perfusion as a function of the tissue perfusion measurement. - View Dependent Claims (16, 17)
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18. A medical method for treating a patient, comprising:
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detecting heart rate as an indicator of inadequate tissue perfusion;
detecting at least one other indicia of inadequate tissue perfusion;
delivering a stimulus to increase tissue perfusion as a function of both heart rate and the at least one other indicia. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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32. A medical method, comprising:
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providing an implantable therapeutic device (ITD) configured to deliver a stimulus to increase heart rate;
providing an implantable pressure sensing device (PSD) including a hermetically sealed housing, a pressure transducer disposed in the housing, a pressure transmission catheter (PTC) having a proximal end, a distal end, and a lumen extending therethrough, with the proximal end of the PTC connected to the housing and the lumen of the PTC in fluid communication with the pressure transducer;
implanting the ITD in a patient;
implanting the PSD in the patient such that the distal end of the PTC resides in a vascular lumen and the housing remains outside the vascular lumen;
connecting the PSD to the ITD via an electrical lead; and
operating the ITD to deliver the stimulus to increase heart rate in response to a drop in blood pressure as measured by the PSD. - View Dependent Claims (33, 34, 35, 36)
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Specification