Systems and methods for a high capture angle, multiple angle light scattering (MALS) instrument
First Claim
1. A system for detecting and identifying a particle in a liquid, the system comprising:
- an optical axis;
a target zone, the optical axis intersecting the target zone;
a reflective optic comprising a curved reflecting surface, the reflective optic index coupled with a liquid medium in the target zone, the reflective optic configured to collect and reflect light scatter by particle in the liquid medium in the target zone;
a detector configured to detect the reflected light; and
a light source configured to generate a light beam and direct the light beam through the target zone.
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Accused Products
Abstract
A particle detection system uses a reflective optic comprising a curved surface to detect high angle scattered light generated by a particle in a liquid medium, when a laser beam is incident on the particle. When the particles transit the laser beam, light is scattered in all directions and is described by MIE scattering theory for particles about the size of the wavelength of light and larger or Rayleigh Scattering when the particles are smaller than the wavelength of light. By using the reflective optic, the scattered light can be detected over angles that are greater than normally obtainable.
45 Citations
26 Claims
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1. A system for detecting and identifying a particle in a liquid, the system comprising:
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an optical axis;
a target zone, the optical axis intersecting the target zone;
a reflective optic comprising a curved reflecting surface, the reflective optic index coupled with a liquid medium in the target zone, the reflective optic configured to collect and reflect light scatter by particle in the liquid medium in the target zone;
a detector configured to detect the reflected light; and
a light source configured to generate a light beam and direct the light beam through the target zone. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A system for detecting and identifying a particle in a liquid, the system comprising:
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an optical axis;
a flow cell comprising a target zone, the optical axis intersecting the target zone;
an interface optic;
a reflective optic comprising a curved reflecting surface, the reflective optic index coupled with a liquid medium in the target zone, the reflective optic configured to collect and reflect light scatter by particle in the liquid medium in the target zone;
a detector configured to detect the reflected light; and
a light source configured to generate a light beam and direct the light beam through the target zone. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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Specification