Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
First Claim
1. A cartridge for use in an analyte detection system comprising:
- a body;
one or more particle-based detection systems positioned on or in the body;
one or more membrane-based detection systems positioned on or in the body; and
one or more channels in the body wherein at least one of the channels is configured to carry one or more fluids to at least one of the particle-based detection systems and to at least one of the membrane-based detection systems.
1 Assignment
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Accused Products
Abstract
Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator'"'"'s contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
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Citations
57 Claims
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1. A cartridge for use in an analyte detection system comprising:
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a body;
one or more particle-based detection systems positioned on or in the body;
one or more membrane-based detection systems positioned on or in the body; and
one or more channels in the body wherein at least one of the channels is configured to carry one or more fluids to at least one of the particle-based detection systems and to at least one of the membrane-based detection systems. - View Dependent Claims (2, 3, 7, 9, 17, 24, 27, 28, 29, 31, 33, 34, 35, 36, 37, 43, 51, 52, 53, 54, 55, 57)
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4-6. -6. (canceled)
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8. (canceled)
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10-16. -16. (canceled)
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18-23. -23. (canceled)
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25-26. -26. (canceled)
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30. (canceled)
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32. (canceled)
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38-42. -42. (canceled)
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44-50. -50. (canceled)
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56. An analyte detection system comprising:
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a cartridge, the cartridge comprising;
a body;
one or more particle-based detection systems positioned in or on the body;
one or more membrane-based detection systems positioned in or on the body; and
one or more channels in the body configured to transport one or more fluids to at least one of the particle-based detection systems and to at least one of the membrane-based detection systems; and
an optical platform optically coupled to at least one of the particle-based detection systems and/or at least one of the membrane-based detection systems.
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Specification