Integration of fluids and reagents into self-contained cartridges containing sensor elements
First Claim
1. A system for detecting an analyte in a sample comprising:
- a sample collection device, wherein the sample collection device is configured to obtain the sample;
a cartridge, wherein the cartridge comprises;
one or more detection systems disposed within the cartridge, wherein at least one of the detection systems is configured to interact with at least a portion of the sample to allow detection of the analyte;
a sample reservoir, wherein the sample collection device is configured to deliver the sample to the sample reservoir; and
wherein the sample is substantially contained in the cartridge during use; and
an optical platform, wherein the optical platform is configured to detect a signal produced by the interaction of the analyte with at least one of the detection systems during use.
1 Assignment
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Accused Products
Abstract
Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator'"'"'s contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
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Citations
135 Claims
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1. A system for detecting an analyte in a sample comprising:
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a sample collection device, wherein the sample collection device is configured to obtain the sample;
a cartridge, wherein the cartridge comprises;
one or more detection systems disposed within the cartridge, wherein at least one of the detection systems is configured to interact with at least a portion of the sample to allow detection of the analyte;
a sample reservoir, wherein the sample collection device is configured to deliver the sample to the sample reservoir; and
wherein the sample is substantially contained in the cartridge during use; and
an optical platform, wherein the optical platform is configured to detect a signal produced by the interaction of the analyte with at least one of the detection systems during use. - View Dependent Claims (4, 6, 10, 26, 29, 33, 41, 43, 44, 48, 51, 53, 54, 55, 56, 57, 58, 61, 62, 71, 72, 73, 78, 79, 80, 81, 82, 89, 90, 135)
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Specification