Systems and methods for non-invasive physiological monitoring of non-human animals

• US 20060258914A1
• Filed: 04/20/2006
• Published: 11/16/2006
• Est. Priority Date: 04/20/2005
• Status: Abandoned Application

• Current Assignee: Adidas AG
• Original Assignee: Adidas AG
• Inventors: Ostertag, Kathryn Lynn, Derchak, P. Alexander
• Application Number:
  US11/407,034
• Publication Number:
  US 20060258914A1
• Time in Patent Office: Days
• US Class Current: 600/300
• CPC Class Codes: A01K 29/005 Monitoring or measuring activity, e.g. detecting heat or mating
• CPC Class Codes: A61B 2503/40 Animals
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/1116 Determining posture transitions
• CPC Class Codes: A61B 5/1118 Determining activity level
• CPC Class Codes: A61B 5/1123 Discriminating type of movement, e.g. walking or running A61B5/1116, A61B5/112 take precedence
• CPC Class Codes: A61B 5/1135 by monitoring thoracic expansion
• CPC Class Codes: A61B 5/335 using integrated circuit memory devices
• CPC Class Codes: A61B 5/4519 Muscles A61B5/389, A61B5/224 take precedence
• CPC Class Codes: A61B 5/6805 Vests

Abstract

This invention provides monitoring garments for non-invasively monitoring physiological parameters in un-restrained and/or restrained animals, such as monkeys, rabbits, dogs, horses, and the like. The invention also includes methods and systems for collecting and processing monitoring data.

Claims

1. An apparatus for monitoring members of a non-human animal species, comprising:

a monitoring garment to be worn by said member animals that is adapted and configured to the size and behavior of said member animals and that permits said member animals to perform normal activities;

one or more sensors incorporated into said garment for sensing physiological functioning of said member animals; and

a portable data unit that is adapted and configured to be carried on said member animals and that activates said sensors and retrieves physiological data from said sensors without wired external connection.

2. The apparatus of claim 1, wherein said monitoring garment further comprises a strap configured to fit about the torso of said member animals.

3. The apparatus of claim 1, wherein said monitoring garment further comprises one or more attachment and/or fitting devices to adjust said monitoring garment to an individual member animal.

4. The apparatus of claim 3, wherein said attachment and/or fitting devices comprise a zipper, a Velcro portion, a drawstring, or an elastic portion.

5. The apparatus of claim 1, wherein said monitoring garment further comprises:

a principal portion sized and configured to fit in a shirt-like fashion around the torso of a member animal; and

one or more open portions for accommodating and encircling at least one extremity of a member animal when said garment is worn by said animal so that motion of the garment relative to the animal is limited.

6. The apparatus of claim 5 further comprising two open portions for accommodating both fore extremities of a member animal when said garment is worn by said animal.

7. The apparatus of claim 5, further comprising one or more attachment devices for securing the principal portion of the monitoring garment around the torso of a member animal.

8. The apparatus of claim 5, further comprising an elastic portion for holding the monitoring garment snugly about the torso of a member animal

9. The apparatus of claim 1, wherein said monitoring garment further comprises at least one pocket.

10. The apparatus of claim 1, wherein said monitoring garment further comprises at least one flap having a fixed edge attached to said garment and a free edge securable to said garment by an attachment device.

11. The apparatus of claim 1, wherein said portable data unit further temporarily stores retrieved sensor data and/or wirelessly transmits retrieved sensor data.

12. The apparatus of claim 1, wherein said portable data unit is carried on or by said animal.

13. The apparatus of claim 1, wherein said sensors comprise one or more sensors responsive to a size of a portion of said member animals.

14. The apparatus of claim 13, wherein at least one of said size sensors is based on inductive plethysmographic technology.

15. The apparatus of claim 13 wherein said size sensors comprise sensors responsive to a size of a rib cage and to a size of the abdomen of said member animals.

16. The apparatus of claim 1, wherein said sensors comprise an accelerometer sensitive to a posture sensor and/or an activity sensor.

17. The apparatus of claim 1, wherein said sensors comprise one or more of an electrocardiogram electrode, a temperature sensor, a blood oxygen level sensor, an electrode for cerebral electrical activity, an electrode for muscle electrical activity, or an electrode for ocular muscles electrical activity.

18. A method for determining cardiac parameters of a non-human animal, comprising:

fitting the non-human animal with a monitoring garment of claim 1;

retrieving cardiac data and respiratory data from said monitoring garment when worn by said non-human animal;

selecting one or more apneic periods during which said retrieved respiratory data indicates that the animal was experiencing a central apnea; and

measuring said cardiac parameters from those portions of said retrieved cardiac data that are concurrent with said selected apneic periods.

19. The method of claim 18, wherein said measured cardiac parameters comprise one or more timing components of an ECG signal.

20. The method of claim 18, wherein said measured cardiac parameters comprise a baseline heart rate.

25. A method for determining dysphoric emotional states in a non-human animal, comprising:

fitting the non-human animal with a monitoring garment of claim 1;

retrieving cardiac data, respiratory data, and activity data from said monitoring garment when worn by said non-human animal;

determining the occurrence or non-occurrence of abnormal physiological and behavioral patterns indicative of the presence of a dysphoric emotion state in said non-human animal.

26. The method of claim 25, wherein said non-human animal is normally active during the day, and wherein said indicative patterns comprise abnormal physiological/behavioral patterns occurring during periods of darkness.

27. The method of claim 25, wherein said indicative patterns comprise periodic repetitions of stereotypical activity, each repetition in association with a similar physiological pattern.

28. The method of claim 25, further comprising treating said non-human animal evidencing stereotypical activity by providing said animal with a new physical and/or social environment.

29. The method of claim 25, further comprising assessing the degree of dysphoria from the magnitude of said abnormal physiological/behavioral patterns and/or from the frequency of said abnormal physiological/behavioral patterns.

30. A method of detecting periods of physiologic rest in a non-human animal, comprising:

fitting the non-human animal with a monitoring garment of claim 1;

retrieving cardiac data, respiratory data, and activity data from said monitoring garment when worn by said non-human animal;

determining the occurrence or non-occurrence of physiological and behavioral patterns indicative of the presence of physiologic rest in said non-human animal.

31. The method of claim 30, wherein said indicative patterns comprise reduced temporal variation in said retrieved physiological data concurrent with reduced levels of physical activity.

32. The method of claim 30, wherein said non-human animal is normally active during the day, and wherein said indicative patterns occur during periods of darkness.

33. The method of claim 30, further comprising determining the relative duration of physiologic rest in said non-human animal.

34. The method of claim 30, further comprising determining periods when said non-human animal is sleeping from said retrieved physiological data.

35. A method of assessing the effects of a pharmacological agent in non-human animals, comprising:

performing in any order the procedures of

(i) fitting the non-human animals with the monitoring garments of claim 1, and retrieving physiological data and activity data from said monitoring garments when worn by said non-human animals to which said pharmacological agent has not been administered; and

(ii) fitting the non-human animals with the monitoring garments of claim 1, and retrieving physiological data and activity data from said monitoring garments when worn by said non-human animals to which said pharmacological agent has been administered; and

comparing said physiological data retrieved in procedures (i) and (ii).

36. The method of claim 35 wherein said pharmacological agent has been administered prior to fitting said monitoring garments to said non-human animals.

21. An apparatus for monitoring a non-human animal, comprising:

a monitoring garment to be worn by said non-human animal that is adapted and configured to the size and behavior of said non-human animal and that permits said non-human animal to perform normal activities;

one or more sensors incorporated into said garment for sensing physiological functioning of said non-human animal;

a portable data unit that is adapted and configured to be carried on said non-human animal and that activates said sensors and retrieves physiological data from said sensors without wired external connection; and

a computer system operatively coupled for data transfer to said portable data unit for displaying said retrieved physiological data.

22. The apparatus of claim 21, wherein said operative coupling comprises computer readable media written by said portable data unit and read by said computer system.

23. The apparatus of claim 21, wherein said operative coupling comprises a wireless communications link.

24. The apparatus of claim 21, wherein said displayed physiological data comprises indicia of respiratory functioning and/or indicia of cardiac functioning and/or indicia of posture and/or activity.