Method and apparatus for cardiac protection pacing
First Claim
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1. A cardiac pacing system, comprising:
- a sensing circuit to sense one or more signals indicative of an ischemic event;
an ischemia detector, coupled to the sensing circuit, to detect the ischemic event from the one or more signals;
a pulse output circuit to deliver pacing pulses; and
a control circuit, coupled to the ischemia detector and the pulse output circuit, to control the delivery of the pacing pulses, the control circuit including;
a cardiac protection pacing sequence initiator adapted to initiate one or more cardiac protection pacing sequences in response to the detection of the ischemic event, the one or more cardiac protection pacing sequences each including alternating pacing and non-pacing periods, the pacing periods each having a pacing duration during which a plurality of the pacing pulses is delivered, the non-pacing periods each having a non-pacing duration during which none of the pacing pulses is delivered; and
a cardiac protection pacing timer adapted to time the one or more cardiac protection pacing sequences.
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Abstract
A pacing system delivers cardiac protection pacing to protect the heart from injuries associated with ischemic events. The pacing system detects an ischemic event and, in response, initiates one or more cardiac protection pacing sequences each including alternative pacing and non-pacing periods. In one embodiment, the pacing system initiates cardiac protection pacing sequences including at least one postconditioning sequence to protect the heart from a detected ischemic event and a plurality prophylactic preconditioning sequences to protect the heart from probable future ischemic events.
188 Citations
40 Claims
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1. A cardiac pacing system, comprising:
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a sensing circuit to sense one or more signals indicative of an ischemic event;
an ischemia detector, coupled to the sensing circuit, to detect the ischemic event from the one or more signals;
a pulse output circuit to deliver pacing pulses; and
a control circuit, coupled to the ischemia detector and the pulse output circuit, to control the delivery of the pacing pulses, the control circuit including;
a cardiac protection pacing sequence initiator adapted to initiate one or more cardiac protection pacing sequences in response to the detection of the ischemic event, the one or more cardiac protection pacing sequences each including alternating pacing and non-pacing periods, the pacing periods each having a pacing duration during which a plurality of the pacing pulses is delivered, the non-pacing periods each having a non-pacing duration during which none of the pacing pulses is delivered; and
a cardiac protection pacing timer adapted to time the one or more cardiac protection pacing sequences. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method for delivering pacing pulses, the method comprising:
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sensing one or more signals indicative of an ischemic event;
detecting the ischemic event from the one or more signals;
initiating one or more cardiac protection pacing sequences in response to the detection of the ischemic event, the one or more cardiac protection pacing sequences each including alternating pacing and non-pacing periods, the pacing periods each having a pacing duration during which a plurality of pacing pulses is delivered, the non-pacing periods each having a non-pacing duration during which no pacing pulse is delivered; and
delivering the plurality of pacing pulses during each of the pacing periods. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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Specification