Medical devices including metallic films and methods for making same
First Claim
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1. An endoprosthesis, comprising:
- first and second tubular frameworks spaced apart by a degradable central portion and defining an interior and an exterior, the tubular frameworks configured to, upon deployment within a body passage, exert a radially expansive force against the body passage sufficient to retain the endoprosthesis with respect to the body passage, the degradable central portion configured to, upon deployment within the body passage, initially reduce a flow of blood between the interior and exterior of the endoprosthesis and, subsequent to deployment, degrade over time providing increased flow of blood between the interior and exterior of the endoprosthesis.
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Abstract
Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film and one or more polymer layers. The polymer layers contribute to mechanical or biological properties of the endoprosthesis.
165 Citations
17 Claims
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1. An endoprosthesis, comprising:
first and second tubular frameworks spaced apart by a degradable central portion and defining an interior and an exterior, the tubular frameworks configured to, upon deployment within a body passage, exert a radially expansive force against the body passage sufficient to retain the endoprosthesis with respect to the body passage, the degradable central portion configured to, upon deployment within the body passage, initially reduce a flow of blood between the interior and exterior of the endoprosthesis and, subsequent to deployment, degrade over time providing increased flow of blood between the interior and exterior of the endoprosthesis. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. An endoprosthesis, comprising:
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a generally tubular deposited metallic film comprising first and second ends and at least one fenestration located therebetween, the at least one fenestration having an area sufficient to pass a microcatheter; and
a degradable layer obstructing the fenestration, the degradable layer configured to, upon deployment of the endoprosthesis within a body passage, degrade thereby opening the fenestration to provide an area sufficient to allow passage of a microcatheter. - View Dependent Claims (9, 10, 11, 12)
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13. A generally tubular endoprosthesis defining an interior and an exterior, the endoprosthesis comprising:
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a deposited metallic film comprising a plurality of fenestrations; and
a degradable polymer layer configured to reduce passage of liquid between the interior of the endoprosthesis and the exterior of the endoprosthesis along a path including the fenestrations. - View Dependent Claims (14, 15, 16, 17)
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Specification