Bioartificial implant and its use and method of reducing the risk for formation of connective tissue after implantation
First Claim
1. A bioartificial implant, comprising, a semipermeable barrier designed from one sides to allow diffusion or prevent diffusion of at least one of substances, materials, molecules, cells, and cell lines produced in the human body to an opposite side of the barrier, and designed from said opposite side to allow diffusion or prevent diffusion of substances which are the same as or different from the substances, materials, molecules, cells, and cell lines, the semipermeable barrier including a surface coating of a bioactive metal, said surface coating being permeable to allow or prevent said diffusions.
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Abstract
A bioartificial implant comprises a semipermeable barrier designed from one side to allow diffusion or prevent diffusion of predetermined substances/materials/molecules/cells/cell lines produced in the human body to the other opposite side of the barrier, and from said other opposite side to allow diffusion or prevent diffusion of predetermined substances which are the same as or different from the first mentioned substances/materials/molecules/cells/cell lines. The semipermeable barrier has a surface coating at least on said one side a bioactive metal, such as titanium, which surface coating is permeable to allow said diffusions. In a method for reducing the risk of formation/growth of connective tissue in connection with an implant which comprises a semipermeable barrier, the barrier is provided at least on one side with a permeable coating of bioactive metal. An example of the use of the implant is bioartificial pancreas.
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Citations
20 Claims
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1. A bioartificial implant, comprising,
a semipermeable barrier designed from one sides to allow diffusion or prevent diffusion of at least one of substances, materials, molecules, cells, and cell lines produced in the human body to an opposite side of the barrier, and designed from said opposite side to allow diffusion or prevent diffusion of substances which are the same as or different from the substances, materials, molecules, cells, and cell lines, the semipermeable barrier including a surface coating of a bioactive metal, said surface coating being permeable to allow or prevent said diffusions.
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2. A bioartificial implants comprising:
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a semipermeable barrier designed from one side, to allow diffusion of body cell nutrient and oxygen from a body of a donee to an opposite side of the barrier where at least one of body organ and cells from a donor are positioned, and designed from said opposite side to allow diffusion of substances selected in advance, produced by at least one of the body organ and cells from the donor, the semipermeable barrier including a surface coating on said one side of a bioactive metal, said surface coating being permeable to allow said diffusions. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 20)
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9. A method for reducing the risk of at least one of formation and growth of connective tissue in connection with an implant including a semipermeable barrier, the method comprising:
providing the barrier, at least on one side, with a permeable coating of bioactive metal. - View Dependent Claims (10)
Specification