Corneal mask formed of degradation resistant polymer and providing reduced corneal deposits
First Claim
1. A mask configured to be implanted in a cornea of a patient, the mask comprising:
- a body formed from a polymeric material, the body having a light transmitting portion, a light blocking portion disposed about the light transmitting portion, an outer periphery surrounding the light blocking portion, an anterior surface, and a posterior surface, the anterior surface configured to reside adjacent a first intracorneal layer, the posterior surface configured to reside adjacent a second intracorneal layer, wherein the polymeric material includes one or more polyanionic compounds loaded into the polymeric material.
1 Assignment
0 Petitions
Accused Products
Abstract
Disclosed are masks configured to be implanted in a cornea of a patient. In one embodiment, the body of the mask has a light transmitting portion, a light blocking portion disposed about the light transmitting portion, and an outer periphery surrounding the light blocking portion. The mask is adapted to reside between two intracorneal layers of a cornea. In a preferred embodiment, the mask is formed from a material comprising a highly fluorinated polymeric material and an opacification agent and is resistant to degradation upon exposure to ultraviolet light. In another embodiment, the mask is formed from a material which comprises a polyanionic compound. In some embodiments, the mask includes one or more wound healing modulator compounds to aid in proper healing following implantation.
186 Citations
65 Claims
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1. A mask configured to be implanted in a cornea of a patient, the mask comprising:
a body formed from a polymeric material, the body having a light transmitting portion, a light blocking portion disposed about the light transmitting portion, an outer periphery surrounding the light blocking portion, an anterior surface, and a posterior surface, the anterior surface configured to reside adjacent a first intracorneal layer, the posterior surface configured to reside adjacent a second intracorneal layer, wherein the polymeric material includes one or more polyanionic compounds loaded into the polymeric material. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A mask configured to be implanted in a cornea of a patient, the mask comprising:
a body formed from a material comprising a highly fluorinated polymeric material, the body having a light transmitting portion, a light blocking portion disposed about the light transmitting portion, and outer periphery surrounding the light blocking portion, an anterior surface, and a posterior surface, the anterior surface configured to reside adjacent a first intracorneal layer, the posterior surface configured to reside adjacent a second intracorneal layer, wherein the material comprising a highly fluorinated polymeric material has loaded therein one or more polyanionic compounds. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. A mask comprising:
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an aperture having a major axis of about 2.2 mm or less; and
an annular body extending between the aperture and an outer periphery of the mask, the annular body having an anterior surface and a posterior surface, the annular body being formed of a material comprising;
a highly fluorinated polymeric material;
an opacification agent, the opacification agent being present in sufficient quantity to prevent at least a substantial portion of light incident on the anterior surface from being transmitted from the anterior surface to the posterior surface; and
one or more polyanionic compounds and/or wound healing modulator compounds. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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51. A mask configured to be implanted in a cornea of a patient, the mask comprising:
a body formed from a polymeric material, the body having a light transmitting portion, a light blocking portion disposed about the light transmitting portion, an outer periphery surrounding the light blocking portion, an anterior surface configured to reside adjacent a first intracorneal layer, a posterior surface configured to reside adjacent a second intracorneal layer, and at least one wound healing modulator loaded in the polymeric material and/or bound to at least one of the anterior surface and the posterior surface. - View Dependent Claims (52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65)
Specification