Method and apparatus for compact spectrometer for multipoint sampling of an object
First Claim
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1. A method of assessing occurrence of an agent in a sample, comprising the steps of:
- (a) illuminating the sample with photons emanating from a portable device to thereby produce Raman-scattered photons from a first set of multiple points in the sample wherein said ones of said first set of multiple points have a defined geometric relationship; and
(b) analyzing the Raman-scattered photons from said first set of multiple points in the sample using the portable device wherein said Raman-scattered photons are characteristic of the presence or absence of the agent in the sample.
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Abstract
The disclosure relates to methods and apparatus for assessing occurrence of one or more hazardous agents in a sample by performing multipoint spectral analysis of the sample using a portable or hand-held device. Methods of employing Raman spectroscopy and other spectrophotometric methods are disclosed. Devices and systems suitable for performing such multipoint methods are also disclosed.
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Citations
60 Claims
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1. A method of assessing occurrence of an agent in a sample, comprising the steps of:
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(a) illuminating the sample with photons emanating from a portable device to thereby produce Raman-scattered photons from a first set of multiple points in the sample wherein said ones of said first set of multiple points have a defined geometric relationship; and
(b) analyzing the Raman-scattered photons from said first set of multiple points in the sample using the portable device wherein said Raman-scattered photons are characteristic of the presence or absence of the agent in the sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A method of identifying an agent in a sample, comprising the steps of:
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(a) illuminating the sample with photons emanating from a portable device to thereby produce Raman-scattered photons from a first set of multiple points in the sample wherein said ones of said first set of multiple points have a defined geometric relationship;
(b) analyzing the Raman-scattered photons from said first set of multiple points in the sample using the portable device; and
(c) comparing the Raman-scattered photons from said first set of multiple points in the sample with a known Raman scattering characteristic of the agent.
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28. A method of assessing viability of an agent in a sample, comprising the steps of:
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(a) illuminating the sample with photons emanating from a portable device to thereby produce Raman-scattered photons from a first set of multiple points in the sample wherein said ones of said first set of multiple points have a defined geometric relationship;
(b) analyzing the Raman-scattered photons from said first set of multiple points in the sample using the portable device; and
(c) comparing the Raman-scattered photons from said first set of multiple points in the sample with a known Raman scattering characteristic of a viable or nonviable form of the agent.
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29. A portable device for assessing occurrence of an agent in a sample, comprising:
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(a) a portable device for illuminating the sample with photons to thereby produce Raman-scattered photons from a first set of multiple points in the sample wherein said ones of said first set of multiple points have a defined geometric relationship; and
(b) means for analyzing the Raman-scattered photons from said first set of multiple points in the sample using the portable device wherein said Raman-scattered photons are characteristic of the presence or absence of the agent in the sample. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58)
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59. A portable device for identifying an agent in a sample, comprising:
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(a) a portable device for illuminating the sample with photons to thereby produce Raman-scattered photons from a first set of multiple points in the sample wherein said ones of said first set of multiple points have a defined geometric relationship;
(b) means for analyzing the Raman-scattered photons from said first set of multiple points in the sample using the portable device wherein said Raman-scattered photons are characteristic of the presence or absence of the agent in the sample; and
(c) means for comparing the Raman-scattered photons from said first set of multiple points in the sample with a known Raman scattering characteristic of the agent.
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60. A portable device for assessing viability of an agent in a sample, comprising:
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(a) a portable device for illuminating the sample with photons to thereby produce Raman-scattered photons from a first set of multiple points in the sample wherein said ones of said first set of multiple points have a defined geometric relationship;
(b) means for analyzing the Raman-scattered photons from said first set of multiple points in the sample using the portable device wherein said Raman-scattered photons are characteristic of the presence or absence of the agent in the sample; and
(c) means for comparing the Raman-scattered photons from said first set of multiple points in the sample with a known Raman scattering characteristic of a viable or nonviable form of the agent.
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Specification