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Water relaxation-based sensors

  • US 20060269965A1
  • Filed: 05/09/2006
  • Published: 11/30/2006
  • Est. Priority Date: 05/09/2005
  • Status: Abandoned Application
First Claim
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1. A water relaxation-based sensor for detecting the presence of an analyte in a sample, the sensor comprising:

  • (i) a walled enclosure enveloping a chamber, wherein the wall comprises an opening for passage of the analyte into and out of the chamber;

    (ii) a plurality of magnetic nanoparticles located within the chamber, each nanoparticle having at least one moiety that is covalently or noncovalently linked to the nanoparticle; and

    optionally, (iii) at least one binding agent located within the chamber;

    wherein the opening is smaller in size than the nanoparticles, and is larger in size than the analyte; and

    wherein the moiety and the analyte each bind reversibly to the binding agent, when present;

    or the analyte binds reversibly to the moiety.

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