Low-Mass Thermal Cycling Block
First Claim
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1. An apparatus for thermally cycling biological samples, the apparatus comprising:
- a thermal block for receiving the biological samples;
a thermoelectric module thermally coupled to the thermal block; and
a heat sink, wherein said heat sink is thermally coupled to the thermoelectric module, wherein the thermal block is produced by MIM.
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Abstract
An apparatus and method for rapid thermal cycling including a thermal block manufactured by metal-injection molding (MIM). The thermal cycling of a biological product can be more rapidly achieved by including a MIM thermal block with a thermoelectric module thermally coupled to the thermal block, a heat sink thermally coupled to the thermoelectric module, and a resistive heater thermally coupled to the thermal block.
18 Citations
20 Claims
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1. An apparatus for thermally cycling biological samples, the apparatus comprising:
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a thermal block for receiving the biological samples;
a thermoelectric module thermally coupled to the thermal block; and
a heat sink, wherein said heat sink is thermally coupled to the thermoelectric module, wherein the thermal block is produced by MIM. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method for thermally cycling biological sample, the method comprising:
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providing a thermal block, wherein the thermal block is produced by MIM process;
heating the thermal block; and
cooling the thermal block;
wherein the heating and cooling provide substantial temperature uniformity throughout a plurality of biological samples contained in a plurality of sample wells. - View Dependent Claims (9, 10, 11, 12, 13, 14)
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15. An apparatus for thermally cycling biological samples, the apparatus comprising:
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means for receiving the biological samples;
means for heating the biological samples; and
means for cooling the biological samples, wherein the heating and cooling provide substantial temperature uniformity throughout a plurality of biological samples contained in a plurality of sample wells, wherein means for receiving the biological samples is produced by MIM. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification