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Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods

  • US 20060271121A1
  • Filed: 05/25/2005
  • Published: 11/30/2006
  • Est. Priority Date: 05/25/2005
  • Status: Abandoned Application
First Claim
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1. A machine-assisted method comprising:

  • measuring a first impedance signal, the first impedance signal including information indicative of a volume of a first ventricle of a heart as the first ventricle expands and contracts during a cardiac cycle;

    using the first impedance signal to measure a peak-to-peak volume difference indicated by a difference between a first impedance value, corresponding to a maximum volume of the first ventricle during a diastole portion of the cardiac cycle, and a second impedance value, corresponding to a minimum volume of the first ventricle during systole portion of the same cardiac cycle; and

    automatically adjusting, using the volume difference, at least one cardiac resynchronization therapy parameter that synchronizes left and right ventricular heart contractions, the automatically adjusting tending to increase the volume difference over at least one subsequent cardiac cycle.

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