Drug-eluting stent cover and method of use
First Claim
1. A method for treating a body lumen with a drug-delivery stent assembly, comprising:
- providing a pattern of struts interconnected to form a stent structure that contacts the walls of a body lumen to maintain the patency of the lumen;
attaching a stent cover having a delivery sheath fabricated from a mesh to at least a portion of an outside surface area of the stent structure to form the stent assembly;
loading the delivery sheath with at least one therapeutic drug for the release thereof in the body lumen;
intraluminally delivering the stent assembly in the body lumen;
providing a radially outward directed force to the stent cover; and
plastically deforming at least a portion of the stent cover in response to the radially outward directed force so that the deformed portions neck down or break thereby providing less resistance to expansion of the stent assembly.
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Accused Products
Abstract
An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.
124 Citations
20 Claims
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1. A method for treating a body lumen with a drug-delivery stent assembly, comprising:
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providing a pattern of struts interconnected to form a stent structure that contacts the walls of a body lumen to maintain the patency of the lumen;
attaching a stent cover having a delivery sheath fabricated from a mesh to at least a portion of an outside surface area of the stent structure to form the stent assembly;
loading the delivery sheath with at least one therapeutic drug for the release thereof in the body lumen;
intraluminally delivering the stent assembly in the body lumen;
providing a radially outward directed force to the stent cover; and
plastically deforming at least a portion of the stent cover in response to the radially outward directed force so that the deformed portions neck down or break thereby providing less resistance to expansion of the stent assembly. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification