×

Ruminant mhc class-i-like fc receptors

  • US 20060272036A1
  • Filed: 02/02/2001
  • Published: 11/30/2006
  • Est. Priority Date: 02/03/2000
  • Status: Abandoned Application
First Claim
Patent Images

1. A method of producing colostrums or milk with enhanced levels of immunoglobulins or proteins fused to immunoglobulin γ

  • -chains or FcRn interacting parts thereof, comprising the steps of transferring an immunoglobulin G (IgG) transporting ruminant Fc receptor (FcRn) α

    -chain DNA molecule through transient or persistent transgenesis into the corresponding ruminant animal for overexpression of the protein expressed by the ruminant FcRn α

    -chain DNA molecule, optionally at concomitant upregulation of the expression of the corresponding β

    2-microglobulin gene, to increase the number of functional receptors in the udder, thereby enhancing the transport of immunoglobulins and/or proteins fused to immunoglobulin γ

    -chains or FcRn interacting parts thereof from, or through, the udder into the colostrums or milk.

View all claims
  • 0 Assignments
Timeline View
Assignment View
    ×
    ×