Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
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Abstract
The invention relates to capsules coated with a polyelectrolyte shell and methods for the production thereof.
46 Citations
60 Claims
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1-50. -50. (canceled)
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51. A method comprising applying a plurality of layers of coating substances to template particles by:
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(a) contacting the template particles with a first coating substance in a fluid reaction medium in a reaction chamber which is limited on at least one side by a filtration membrane, under conditions with which a layer of the first coating substance is formed on the template particles;
(b) draining at least part of the reaction medium with, where appropriate, excess first coating substance present therein through the filtration membrane into a filtrate chamber;
(c) contacting the template particles with a second coating substance in a fluid reaction medium in a reaction chamber which is limited on at least one side by a filtration membrane, under conditions with which a layer of the second coating substance is formed on the template particles;
(d) draining at least part of the reaction medium with, where appropriate, excess second coating substance present therein through the filtration membrane into a filtrate chamber; and
(e) optionally repeating steps (a) and (b) or steps (c) and (d) a plurality of times. - View Dependent Claims (52, 53, 54, 55, 56, 57, 58, 59, 60)
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Specification