Tanaproget compositions containing ethinyl estradiol
First Claim
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1. A pharmaceutical composition comprising an effective amount of micronized tanaproget, or a pharmaceutically acceptable salt thereof, and an effective amount of ethinyl estradiol.
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Abstract
Compositions containing micronized tanaproget, or a pharmaceutically acceptable salt thereof, and ethinyl estradiol and methods of preparing the same are provided. Also provided are kits containing the compositions, methods of contraception and hormone replacement therapy including administering a composition containing micronized tanaproget and ethinyl estradiol.
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Citations
30 Claims
- 1. A pharmaceutical composition comprising an effective amount of micronized tanaproget, or a pharmaceutically acceptable salt thereof, and an effective amount of ethinyl estradiol.
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19. A process for preparing an oral composition comprising micronized tanaproget, or a pharmaceutically acceptable salt thereof, comprising:
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(a) mixing said micronized tanaproget, or a pharmaceutically acceptable salt thereof, and ethinyl estradiol; and
(b) granulating the product of step (a). - View Dependent Claims (20, 21, 22, 23, 24)
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25. A pharmaceutically useful kit which comprises:
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(a) a first phase of 14 to 21 daily dosage units of a formulation comprising tanaproget and ethinyl estradiol; and
(b) a second phase of 0 to 7 daily dosage units of an orally and pharmaceutically acceptable placebo;
wherein the total number of the daily dosage units is 28. - View Dependent Claims (26, 27, 28)
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Specification