Ratiometric test strip and method
First Claim
1. A system for monitoring salt intake by a subject without laboratory facilities comprising:
- (i) a monitor strip;
(ii) a filtration strip; and
(iii) a sample of said subject'"'"'s urine.
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Accused Products
Abstract
The invention generally relates to devices, systems and methods adapted for use by patients for monitoring their own dietary intake of sodium without any need of laboratory facilities or collection of blood samples. The systems utilize test strips for measuring the concentration of analytes in urine, specifically, chloride and creatinine. Urinary chloride concentrations, normalized by creatinine concentrations to reduce variability contributed mainly by changing states of hydration serve as a conveniently monitored surrogate for salt intake by subjects, especially patients with hypertension or congestive heart failure who must control their salt intake carefully.
41 Citations
21 Claims
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1. A system for monitoring salt intake by a subject without laboratory facilities comprising:
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(i) a monitor strip;
(ii) a filtration strip; and
(iii) a sample of said subject'"'"'s urine. - View Dependent Claims (2, 3, 4, 5, 6, 7, 9, 10, 13, 14)
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8. A method of monitoring salt intake performed without laboratory facilities, comprising:
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a) providing a first test strip capable of detecting chloride in urine, a second test strip capable of detecting creatinine in urine, and said patient'"'"'s urine;
b) introducing said first and second test strips to said urine so as to obtain first and second values; and
c) calculating a ratio of said first and second values and finding a salt intake value therefrom. - View Dependent Claims (11, 12)
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15. A method of monitoring salt intake without laboratory facilities, comprising:
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a) providing a device comprising a first test region capable of detecting chloride in urine, a second test region capable of detecting creatinine in urine, said first and second regions on a single test strip, and said patient'"'"'s urine;
b) introducing said first and second regions to said urine so as to obtain first and second values; and
c) calculating a ratio of said first and second values and finding a salt intake value therefrom.
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- 16. A device comprising a first test region capable of detecting chloride in urine, a second test region capable of detecting creatinine in urine.
Specification