Non-optical reading of test zones

• US 20060281193A1
• Filed: 06/09/2005
• Published: 12/14/2006
• Est. Priority Date: 06/09/2005
• Status: Abandoned Application

• Current Assignee: Alverix, Inc. (Becton, Dickinson & Co)
• Original Assignee: Alverix, Inc. (Becton, Dickinson & Co)
• Inventors: Schembri, Carol T., Petrilla, John F., Robrish, Peter R.
• Application Number:
  US11/148,623
• Publication Number:
  US 20060281193A1
• Time in Patent Office: Days
• US Class Current: 436/514
• CPC Class Codes: G01N 33/54388 based on lateral flow
• CPC Class Codes: G01N 33/558 using diffusion or migration of antigen or antibody immunochromatographic test strips G01N33/54387

Abstract

A test zone is read. Conjugate material is exposed to a sample. The conjugate material, when conjugated with at least one analyte in the sample, forms either electrically detectable conjugated material or magnetically detectable conjugated material. Conjugated material in the sample is captured in a test zone. A test is performed on the conjugated material captured in the test zone in order to detect analyte in the sample. The test is an electrical measurement, or a magnetic measurement.

Claims

1. A method for reading test zones comprising:

exposing conjugate material to a sample, the conjugate material when conjugated with at least one analyte within the sample forms one of the following types of conjugated material;

electrically detectable conjugated material,

magnetically detectable conjugated material;

capturing in a test zone, conjugated material that results from the sample being exposed to the conjugate material; and

,

performing at least one of the following types of measurements on the conjugated material captured in the test zone in order to detect analyte;

an electrical measurement,

a magnetic measurement.

2. A method as in claim 1 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is an electrical measurement that measures impedances.

3. A method as in claim 1 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is an electrical measurement that measures permittivity attributes.

4. A method as in claim 1 wherein detecting analyte includes determining analyte concentration in the sample.

5. A method as in claim 1 wherein the conjugated material is magnetically detectable conjugated material and the type of measurement to detect analyte is a magnetic measurement that measures permeability attributes.

6. A method as in claim 1 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is an electrical measurement that measures impedances of a daisy chain of test zones.

7. A method as in claim 1 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is a measurement where permittivity or permeability attributes control a measured oscillation signal characteristic.

8. A method as in claim 1 wherein when performing one of the types of measurements to detect analyte, at least one control zone is used for comparative measurements.

9. A testing system comprising:

conjugate material that when conjugated with analyte forms one of the following types of conjugated material;

electrically detectable conjugated material,

magnetically detectable conjugated material;

a test zone in which are captured conjugated material formed when the conjugate material is conjugated with the analyte; and

,

measurement circuitry that performs at least one of the following types of measurements on the captured conjugated material in the test zone in order to detect analyte;

an electrical measurement,

a magnetic measurement.

10. A testing system as in claim 9 additionally comprising a control zone used for comparative measurements.

11. A testing system as in claim 9 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is an electrical measurement that measures impedances.

12. A testing system as in claim 9 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is an electrical measurement that measures permittivity.

13. A testing system as in claim 9 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is an electrical measurement that measures capacitance using a fringe capacitor.

14. A testing system as in claim 9 wherein the conjugated material is magnetically detectable conjugated material and the type of measurement to detect analyte is a magnetic measurement that measures permeability attributes.

15. A testing system as in claim 9 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is an electrical measurement that measures impedances through a daisy chain of test zones.

16. A testing system as in claim 9 wherein the conjugated material is electrically detectable conjugated material and the type of measurement to detect analyte is a measurement where permittivity or permeability attributes control a measured oscillation signal characteristic.

17. A testing system as in claim 9 wherein the conjugate material conjugates with additional analytes allowing testing for multiple analytes.

18. A testing system as in claim 9 wherein the conjugate material is stored in a conjugate pad of a test strip.

19. A testing system as in claim 9 wherein the test zone is a capture line on a test strip.

20. A testing system as in claim 9 additionally comprising a control zone used for comparative measurements;

wherein the test zone is a capture line on a test strip; and

,

wherein the control zone is a control line on the test strip.