Low-lactose partially hydrolyzed infant formula

• US 20060286252A1
• Filed: 06/01/2005
• Published: 12/21/2006
• Est. Priority Date: 06/01/2005
• Status: Active Grant

• Current Assignee: Mead Johnson Nutrition Company (Reckitt Benckiser Group PLC)
• Original Assignee: Mead Johnson Nutrition Company (Reckitt Benckiser Group PLC)
• Inventors: Rangavajla, Nagendra, Chiang, Win-Chin, Burns, Robert A., Vanderhoof, Jon, Wynsen, David A., Puski, Gabor, Khatib, Khaled A.
• Granted Patent: US 7,618,669 B2
• Time in Patent Office: Days
• US Class Current: 426/580
• CPC Class Codes: A23J 3/34 using enzymes
• CPC Class Codes: A23L 33/18 Peptides; Protein hydrolysates
• CPC Class Codes: A23L 33/19 Dairy proteins
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/304 having a modulation effect on allergy and risk of allergy
• CPC Class Codes: A23V 2250/0612 Carnitine
• CPC Class Codes: A23V 2250/0644 Taurine
• CPC Class Codes: A23V 2250/1578 Calcium
• CPC Class Codes: A23V 2250/1592 Iron
• CPC Class Codes: A23V 2250/1612 Manganese
• CPC Class Codes: A23V 2250/1626 Selenium
• CPC Class Codes: A23V 2250/1642 Zinc
• CPC Class Codes: A23V 2250/1862 Arachidonic acid
• CPC Class Codes: A23V 2250/1868 Docosahexaenoic acid
• CPC Class Codes: A23V 2250/54246 Casein
• CPC Class Codes: A23V 2250/54252 Whey protein
• CPC Class Codes: A23V 2250/612 Lactose
• CPC Class Codes: A23V 2250/641 Inositol
• CPC Class Codes: A23V 2250/70 Vitamins
• CPC Class Codes: A23V 2300/28 : Hydrolysis, degree of hydrolysis
• CPC Class Codes: C12Y 304/24028 : Bacillolysin (3.4.24.28)
• CPC Class Codes: Y10S 426/801 : Pediatric

Abstract

The present invention relates to a low-lactose, partially hydrolyzed infant formula. The carbohydrate component of the infant formula comprises between 0% and 60% lactose and the protein component of the infant formula comprises partially hydrolyzed whey protein and casein, the protein component having a particular molecular weight.

Claims

1. An infant formula comprising:

a carbohydrate component which is comprised of between about 0% and 60% lactose, based on the total weight of the carbohydrates present in the infant formula; and

a protein component which is comprised of partially hydrolyzed whey protein and casein, wherein the ratio of whey protein to casein is between about 50;

50 and 70;

30 and wherein the protein hydrolysate has the peptides spread over the following range of molecular weight distribution as a function of their molar mass;

Molar Mass% Molecular Weight(in Daltons)Distribution<

50011-20 

500-100025-381000-200027-302000-3000 

8-163000-5000 

3-10>

5000 

2-11

2. The infant formula according to claim 1, wherein the protein hydrolysate has the peptides spread over the following molecular weight distribution as a function of their molar mass:

3. The infant formula according to claim 1, wherein the ratio of whey protein:

casein is about 60;

40.

4. The infant formula according to claim 1, wherein the carbohydrate component comprises between about 15% and 55% lactose.

5. The infant formula according to claim 1, wherein the carbohydrate component comprises between about 20% and 30% lactose.

6. The infant formula according to claim 1, wherein the carbohydrate component comprises about 25% weight percent lactose and about 75% weight percent corn syrup solids.

7. The infant formula according to claim 1, wherein the degree of hydrolysis of the protein component is between about 4% and 10%.

8. The infant formula according to claim 6, wherein the degree of hydrolysis of the protein component is between about 6% and 9%.

9. The infant formula according to claim 1, wherein the infant formula additionally comprises at least one probiotic.

10. The infant formula according to claim 1, wherein the infant formula additionally comprises at least one prebiotic.

11. The infant formula according to claim 1, wherein the infant formula additionally comprises a LCPUFA.

12. The infant formula according to claim 11, wherein the LCPUFA comprises DHA or ARA.

13. The infant formula according to claim 11, wherein the LCPUFA comprises DHA in an amount of between about 3 mg per kg of body weight per day to about 150 mg per kg of body weight per day.

14. The infant formula according to claim 11, wherein the LCPUFA comprises ARA in an amount of between about 5 mg per kg of body weight per day to about 150 mg per kg of body weight per day.

15. The infant formula according to claim 10, wherein the LCPUFA comprises DHA and ARA.

16. The infant formula according to claim 14, wherein the ratio of ARA:

DHA is from about 1;

3 to about 9;

1.

17. The infant formula according to claim 14, wherein the ratio of ARA:

DHA is from about 1;

2 to about 4;

1.

18. The infant formula according to claim 14, wherein the ratio of ARA:

DHA is from about 2;

3 to about 2;

1

19. The infant formula according to claim 1, wherein the infant formula is in powdered form.

20. The infant formula according to claim 1, wherein the infant formula is in liquid form.

21. A method for preventing the onset of allergies in a subject, the method comprising administering to the subject an infant formula according to claim 1.