Device, system, and method for epithelium protection during cornea reshaping

• US 20060287662A1
• Filed: 05/25/2006
• Published: 12/21/2006
• Est. Priority Date: 05/26/2005
• Status: Abandoned Application

• Current Assignee: NTK Enterprises, Inc.
• Original Assignee: NTK Enterprises, Inc.
• Inventors: Woodward, Benjamin W., Berry, Michael J.
• Application Number:
  US11/440,794
• Publication Number:
  US 20060287662A1
• Time in Patent Office: Days
• US Class Current: 606/166
• CPC Class Codes: A61F 2009/00853 Laser thermal keratoplasty or radial keratotomy
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 2009/00882 based on topography
• CPC Class Codes: A61F 2009/00895 Presbyopia
• CPC Class Codes: A61F 9/0079 using non-laser electromagnetic radiation, e.g. non-coherent light or microwaves
• CPC Class Codes: A61F 9/009 Auxiliary devices making contact with the eyeball and coupling in laser light, e.g. goniolenses apparatus for eye examination A61B3/0008

Abstract

A system includes a light source operable to generate light energy for a cornea reshaping procedure. The system also includes a device operable to be attached to an eye having a cornea. The device includes a window operable to contact at least a portion of the cornea. The window is substantially transparent to the light energy that irradiates the cornea during the cornea reshaping procedure. The window is also operable to cool at least a portion of a corneal epithelium in the cornea during the cornea reshaping procedure. The window may be operable to prevent clinically significant damage to the corneal epithelium during the cornea reshaping procedure. The window may be operable to prevent a temperature of the corneal epithelium from exceeding a damage threshold temperature during the cornea reshaping procedure, such as a damage threshold temperature of approximately 70° C.

Claims

1. A device, comprising:

a suction ring operable to attach the device to an eye, the eye comprising a cornea; and

a window operable to contact at least a portion of the cornea, the window substantially transparent to light energy that irradiates the cornea during a cornea reshaping procedure, the window also operable to cool at least a portion of a corneal epithelium in the cornea during the cornea reshaping procedure.

2. The device of claim 1, wherein the window is operable to prevent clinically significant damage to the corneal epithelium during the cornea reshaping procedure.

3. The device of claim 1, wherein the window is operable to prevent a temperature of the corneal epithelium from exceeding a damage threshold temperature during the cornea reshaping procedure.

4. The device of claim 3, wherein the damage threshold temperature comprises a temperature of approximately 70°

C.

5. The device of claim 1, wherein the window is operable to maintain at least a portion of the cornea at a desired initial temperature prior to irradiation of the cornea.

6. The device of claim 1, wherein the window is operable to partially or completely applanate at least the contacted portion of the cornea.

7. The device of claim 6, wherein the window comprises a planar corneal engaging surface operable to completely applanate at least the contacted portion of the cornea.

8. The device of claim 6, wherein the window comprises a concave corneal engaging surface having a radius of curvature or multiple radii of curvature greater than a radius of curvature or multiple radii of curvature of the cornea and operable to partially applanate at least the contacted portion of the cornea.

9. The device of claim 6, wherein the window comprises a concave corneal engaging surface having a radius of curvature or multiple radii of curvature substantially equal to a desired final radius of curvature or multiple radii of curvature of the cornea and operable to partially applanate at least the contacted portion of the cornea and to provide a template to facilitate cornea reshaping.

10. The device of claim 1, wherein the window has a shape that results in a more prolate aspherical shape of the cornea after the cornea reshaping procedure, the cornea having annular zones of refraction that provide both distance and near visual acuity after the cornea reshaping procedure.

11. The device of claim 1, further comprising a mask operable to restrict irradiation of one or more specified portions of the cornea.

12. The device of claim 1, further comprising a focusing and centration aid operable to facilitate accurate delivery of the light energy onto the cornea.

13. The device of claim 12, wherein the focusing and centration aid comprises a first magnet operable to attract a second magnet in a fiber optic holder.

14. The device of claim 1, further comprising an array of microlenses on the window, the array of microlenses operable to change a spatial distribution of the light energy.

15. The device of claim 1, wherein the window is operable to at least partially reduce evaporation of a film between the window and the eye during the cornea reshaping procedure.

16. The device of claim 1, further comprising a vacuum port operable to be connected to a vacuum source, the vacuum source operable to create a pressure differential along the suction ring to provide suction along the suction ring.

17. The device of claim 1, wherein:

the window comprises one or more of;

sapphire, infrasil quartz, calcium fluoride, and diamond; and

the suction ring comprises one of;

titanium and plastic.

18. The device of claim 1, further comprising one or more cooling elements operable to cool the window during the cornea reshaping procedure.

19. The device of claim 18, wherein the one or more cooling elements comprise:

a reservoir operable to hold a liquid;

a valve operable to release the liquid from the reservoir; and

a nozzle operable to spray the released liquid onto the window to cool to window.

20. The device of claim 1, wherein the light energy comprises light energy from one of:

a pulsed laser and a continuous wave laser.

21. The device of claim 1, wherein the light energy comprises light energy from a laser having one of:

an output wavelength in a range of 1.4 to 1.6 microns;

an output wavelength in a range of 1.8 to 2.1 microns;

an output wavelength in a range of 2.4 to 2.67 microns; and

an output wavelength in a range of 3.8 to 7.0 microns.

22. A system, comprising:

a light source operable to generate light energy for a cornea reshaping procedure; and

a device operable to be attached to an eye comprising a cornea, the device comprising a window operable to contact at least a portion of the cornea, the window substantially transparent to the light energy that irradiates the cornea during the cornea reshaping procedure, the window also operable to cool at least a portion of a corneal epithelium in the cornea during the cornea reshaping procedure.

23. The system of claim 22, wherein the window is operable to prevent clinically significant damage to the corneal epithelium during the cornea reshaping procedure.

24. The system of claim 22, wherein the window is operable to prevent a temperature of the corneal epithelium from exceeding a damage threshold temperature during the cornea reshaping procedure.

25. The system of claim 22, wherein the window is operable to maintain at least a portion of the cornea at a desired initial temperature prior to irradiation of the cornea.

26. The system of claim 22, wherein the window is operable to partially or completely applanate at least the contacted portion of the cornea.

27. The system of claim 22, wherein the window has a shape that results in a more prolate aspherical shape of the cornea after the cornea reshaping procedure, the cornea having annular zones of refraction that provide both distance and near visual acuity after the cornea reshaping procedure.

28. The system of claim 22, wherein:

the device further comprises a suction ring and a vacuum port; and

the system further comprises a vacuum source operable to create a pressure differential along the suction ring to provide suction along the suction ring.

29. The system of claim 22, further comprising:

a plurality of optical fibers operable to transport the light energy from the light source to the device; and

a fiber optic holder, the plurality of optical fibers mounted on the fiber optic holder.

30. The system of claim 29, wherein the device further comprises a focusing and centration aid for facilitating accurate delivery of the light energy onto the cornea.

31. The system of claim 30, wherein:

the focusing and centration aid comprises a first magnet;

the fiber optic holder comprises a second magnet; and

the first and second magnets are operable to attract one another.

32. The system of claim 22, wherein the device further comprises an array of microlenses on the window, the array of microlenses operable to change a spatial distribution of the light energy.

33. The system of claim 22, further comprising:

a fiber optic array operable to transport the light energy to the device, the fiber optic array comprising a plurality of fiber optic cables;

a translation stage operable to move the fiber optic array so that the light energy enters different ones of the fiber optic cables; and

a positioning controller operable to control the translation stage.

34. The system of claim 33, further comprising a system controller operable to control operation of the positioning controller and a power supply.

35. The system of claim 22, further comprising a beam splitting system operable to receive a main beam of light energy from the light source and split the main beam into multiple beamlets of light energy, the cornea irradiated by the multiple beamlets.

36. The system of claim 35, wherein the beam splitting system comprises:

at least one of;

one or more windows and one or more perforated beam splitters operable to split the main beam into the multiple beamlets; and

one or more mirrors operable to redirect at least one of the beamlets.

37. The system of claim 22, wherein the light source comprises one of:

a pulsed laser and a continuous wave laser.

38. The system of claim 22, wherein the light source comprises a laser having one of:

an output wavelength in a range of 1.4 to 1.6 microns;

an output wavelength in a range of 1.8 to 2.1 microns;

an output wavelength in a range of 2.4 to 2.67 microns; and

an output wavelength in a range of 3.8 to 7.0 microns.

39. A method, comprising:

attaching a device to an eye, the eye comprising a cornea, the device comprising a window operable to contact at least a portion of the cornea;

irradiating at least part of the cornea using light energy that passes through the window during a cornea reshaping procedure, the window substantially transparent to the light energy; and

cooling at least a portion of a corneal epithelium in the cornea using the window during the cornea reshaping procedure.