Diagnostic radio frequency identification sensors and applications thereof
First Claim
1. A diagnostics system comprising:
- a flexible patch having an adhesive portion and adapted to be positioned on a surface;
a radio frequency identification (RFID) tag and sensor module integrated with said patch and having an antenna, an RFID electronic chip, and at least one sensor, said RFID tag and sensor module responding to a stimulus by wirelessly transmitting and receiving, through the use of said antenna, signals that correspond to said stimulus; and
a wireless RFID reader adapted to communicate through the use of multiple protocols with said RFID tag and sensor module, said RFID reader being adapted to communicate over a network through the use of multiple communication protocols.
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Accused Products
Abstract
An integrated passive wireless chip diagnostic sensor system is described that can be interrogated remotely with a wireless device such as a modified cell phone incorporating multi-protocol RFID reader capabilities (such as the emerging Gen-2 standard) or Bluetooth, providing universal easy to use, low cost and immediate quantitative analyses, geolocation and sensor networking capabilities to users of the technology. The present invention can be integrated into various diagnostic platforms and is applicable for use with low power sensors such as thin films, MEMS, electrochemical, thermal, resistive, nano or microfluidic sensor technologies. Applications of the present invention include on-the-spot medical and self-diagnostics on smart skin patches, Point of Care (POC) analyses, food diagnostics, pathogen detection, disease-specific wireless biomarker detection, remote structural stresses detection and sensor networks for industrial or Homeland Security using low cost wireless devices such as modified cell phones.
476 Citations
64 Claims
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1. A diagnostics system comprising:
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a flexible patch having an adhesive portion and adapted to be positioned on a surface;
a radio frequency identification (RFID) tag and sensor module integrated with said patch and having an antenna, an RFID electronic chip, and at least one sensor, said RFID tag and sensor module responding to a stimulus by wirelessly transmitting and receiving, through the use of said antenna, signals that correspond to said stimulus; and
a wireless RFID reader adapted to communicate through the use of multiple protocols with said RFID tag and sensor module, said RFID reader being adapted to communicate over a network through the use of multiple communication protocols. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. A human diagnostics system comprising:
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a patch having a radio frequency identification (RFID) tag and sensor module, and being attachable to the surface of the skin and adapted to sense predetermined elements through the skin and transmit signals corresponding to said predetermined elements;
a RFID reader communicative with said patch through the use of a network and adapted to analyze, receive, and transmit the signals from said patch through the use of multiple protocols; and
a remote storage and data unit communicative with said RFID reader, said remote storage and data unit analyzing and storing data from said patch and said RFID, said remote storage and data unit transmitting said analyzed and stored data to said RFID reader through the use of said network. - View Dependent Claims (26, 27, 28, 29)
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30. A personal wireless communications device for communicating with a radio frequency identification (RFID) tag and sensor module, comprising:
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a multi protocol RFID reader that is compatible with and adapted to activate said RFID tag and sensor module;
a microprocessor communicative with said RFID reader and adapted to analyze and store data read by said RFID reader; and
at least one antenna coupled to said microprocessor for transmitting and receiving data from said RFID reader, said microprocessor and said RFID tag and sensor module, said antenna being adapted to transmit and receive data from an external device through the use of a network. - View Dependent Claims (31, 32, 33, 34)
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35. A diagnostics system comprising:
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a patch having an adhesive portion and adapted to be embedded within a structure;
a radio frequency identification (RFID) tag and sensor module having an integrated temperature module, said RFID tag and sensor module being integrated with said patch and having an antenna and at least one sensor, said RFID tag and sensor module responding to a stimulus by wirelessly transmitting and receiving, through the use of said antenna, signals that correspond to said stimulus; and
a wireless RFID reader communicative with said RFID tag and sensor module, said reader being adapted to communicate over a network through the use of multiple protocols. - View Dependent Claims (36, 37)
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38. An immunoassay test strip system for use in conducting diagnostic measurements comprising:
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a substrate that forms a test strip;
at least one test area located on said substrate for capturing antigens; and
a radio frequency identification (RFID) tag and sensor module integrated with said substrate, said RFID tag and sensor module being adapted to sense and transmit signals that correspond to the antigens captured by said at least one test area. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47)
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48. A method of manufacturing a pathogen-specific radio frequency identification (RFID) tag and sensor module, comprising the steps of:
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providing a substrate;
printing conductive leads on said substrate wherein said conductive leads define a sensor area;
printing a protective cap doped with a material that is sensitive to pathogen-specific enzymatic action within said sensor area;
printing an antenna on said substrate; and
integrating an RFID tag and sensor module with said substrate.
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49. A multi-function personal wireless communications device capable of wireless diagnostics through communication with at least one radio frequency (RF) addressable sensor having a radio frequency identification tag and sensor unit, comprising:
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a user interface for receiving an input from a user and transmitting signals corresponding to said input;
a multi-protocol RF reader adapted to receive said input signal, said RF reader adapted to retrieve a unique identification of the RF addressable sensor and downloading software that enables reading and analyses of the RF addressable sensor;
a controller having memory storage and being adapted to process and transmit signals received by said RF reader; and
at least one antenna configured to receive signals from the RF addressable sensor and transmit signals from said controller and said RF reader. - View Dependent Claims (50, 51, 52, 53, 54, 55, 56, 57, 58)
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59. A Lab-on-a-Chip microfluidics sensor for conducting rapid diagnostic measurements that are readable directly with a remote wireless RF reader comprising:
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conductive leads that enable transmission of signals;
a Lab-on-a-Chip substrate having at least one test area integrated therein and a sensor interface that couples said conductive leads to said test area;
a temperature module integrated with said substrate and adapted to generate signals that correspond to temperature;
an addressable radio frequency (RF) chip having a controller, an RF power source with a voltage stabilization circuit, and a communication interface, said RF chip receiving signals from said conductive leads and said temperature module, said RF chip being adapted to process said conductive lead signals, said temperature module signals and signals from the wireless RF reader; and
at least one antenna adapted to receive signals from the wireless RF reader and said RF chip and transmit signals from said Lab-on-a-Chip microfluidics sensor. - View Dependent Claims (60, 61, 62)
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63. An immunoassay test strip for conducting an instant diagnostics test using a wireless reader device, wherein the wireless reader device is adapted to communicate over a wireless network, the immunoassay test strip comprising:
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at least one test area with an integrated radio frequency chip that is communicative with the wireless device and that provides power to said test area; and
wherein said test area is an electro-immunoassay for measuring the presence and quantity of a biological molecule. - View Dependent Claims (64)
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Specification