Salmeterol and ciclesonide combination
First Claim
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1. A pharmaceutical composition comprising ciclesonide or a pharmaceutically acceptable salt or solvate thereof or a physiologically functional derivative of ciclesonide or solvate thereof and salmeterol or a pharmaceutically acceptable salt or solvate thereof or a physiologically functional derivative of salmeterol or solvate thereof, and a pharmaceutically acceptable carrier and/or one or more excipients, and optionally one or more other therapeutic ingredients.
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Abstract
The invention relates to pharmaceutical compositions containing combinations of salmeterol and ciclesonide and the use of such pharmaceutical compositions in medicine, in particular, the prophylaxis and treatment of respiratory disease.
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Citations
22 Claims
- 1. A pharmaceutical composition comprising ciclesonide or a pharmaceutically acceptable salt or solvate thereof or a physiologically functional derivative of ciclesonide or solvate thereof and salmeterol or a pharmaceutically acceptable salt or solvate thereof or a physiologically functional derivative of salmeterol or solvate thereof, and a pharmaceutically acceptable carrier and/or one or more excipients, and optionally one or more other therapeutic ingredients.
- 8. A pharmaceutical aerosol composition comprising particles of salmeterol in a therapeutically effective amount and a therapeutically effective amount of ciclesonide and a hydrofluorocarbon propellant, and a cosolvent in an amount effective to solubilize ciclesonide and optionally a surfactant.
- 10. A pharmaceutical aerosol composition comprising particles of salmeterol in a therapeutically effective amount and particles of ciclesonide in a therapeutically effective amount and a hydrofluorocarbon propellant, and 0.01 to 5% w/w based upon propellant of polar cosolvent and optionally a surfactant.
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12. A method for the treatment of a clinical condition in a mammal for which a selective β
- 2-adrenoreceptor agonist and/or glucocorticosteroid is indicated, which comprises administering a therapeutically effective amount of a pharmaceutical formulation comprising salmeterol or a pharmaceutical acceptable salt or solvate thereof, or a physiologically functional derivative of salmeterol or a solvate thereof, and ciclesonide or a pharmaceutical acceptable salt or solvate thereof, or a physiologically functional derivative of ciclesonide or a solvate thereof, and a pharmaceutical acceptable carrier and/or one or more excipients.
- View Dependent Claims (13, 14, 15, 16)
Specification