Pyridine nucleotide dehydrogenase based biosensor electrodes
First Claim
1. An electrode for the electrochemically reversible interconversion of the oxidised and reduced versions of a pyridine nucleotide comprising:
- an electrically conducting surface;
an isolated pyridine nucleotide dehydrogenase module of an enzyme;
wherein said isolated pyridine nucleotide dehydrogenase module is applied to the electrically conducting surface.
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Abstract
The invention provides an electrode for the electrochemically reversible interconversion of the oxidised and reduced versions of a pyridine nucleotide comprising: an electrically conducting surface; an isolated pyridine nucleotide dehydrogenase module of an enzyme; wherein said isolated pyridine nucleotide dehydrogenase module is applied to the electrically conducting surface. The isolated pyridine nucleotide dehydrogenase module may be the Iλ subcomplex of bovine mitochondrial NADH: ubiquinone oxidoreductase. Electrochemical cells comprising these electrodes are also provided by the invention.
8 Citations
30 Claims
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1. An electrode for the electrochemically reversible interconversion of the oxidised and reduced versions of a pyridine nucleotide comprising:
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an electrically conducting surface;
an isolated pyridine nucleotide dehydrogenase module of an enzyme;
wherein said isolated pyridine nucleotide dehydrogenase module is applied to the electrically conducting surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification