Determination of the clinical state of a subject
First Claim
1. A method for determining a clinical state of a subject, the method comprising the steps of:
- acquiring at least one measurement signal containing physiological data from the subject;
subjecting the at least one measurement signal to an adaptive transform to obtain at least one transformed measurement signal, the adaptive transform being dependent on previously acquired history data;
forming a diagnostic index which is dependent on the at least one transformed measurement signal, the diagnostic index serving as a measure of the clinical state of the subject; and
replacing at least part of the previously acquired history data on which the adaptive transform is currently dependent with other previously acquired history data, the replacing step being performed when a predetermined event is detected.
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Abstract
The invention relates to the determination of the clinical state of a subject. A respective adaptive transform is applied to at least one measurement signal acquired from the subject, each adaptive transform being dependent on previously acquired history data, and a diagnostic index is formed, which is dependent on the transformed measurement signal(s) and serves as a measure of the clinical state of the subject. In order to reliably evaluate the clinical state of a subject on a fixed diagnostic scale during changes in the state of the subject, some or all of the previously acquired history data on which an adaptive transform is currently dependent is replaced with other previously acquired history data when a predetermined event is detected. The predetermined event is indicative of a change in the respective measurement signal, and the introduction of the said other previously acquired history data sets the transform ready for the change.
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Citations
21 Claims
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1. A method for determining a clinical state of a subject, the method comprising the steps of:
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acquiring at least one measurement signal containing physiological data from the subject;
subjecting the at least one measurement signal to an adaptive transform to obtain at least one transformed measurement signal, the adaptive transform being dependent on previously acquired history data;
forming a diagnostic index which is dependent on the at least one transformed measurement signal, the diagnostic index serving as a measure of the clinical state of the subject; and
replacing at least part of the previously acquired history data on which the adaptive transform is currently dependent with other previously acquired history data, the replacing step being performed when a predetermined event is detected. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. An apparatus for determining a clinical state of a subject, the apparatus comprising:
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measurement means for acquiring at least one measurement signal containing physiological data from the subject;
transform means for subjecting at least one measurement signal to an adaptive transform to obtain at least one transformed measurement signal, the adaptive transform being dependent on previously acquired history data;
means for forming a diagnostic index which is dependent on the at least one transformed measurement signal, the diagnostic index serving as a measure of the clinical state of the subject;
first monitoring means for detecting a predetermined event; and
control means for replacing at least part of the previously acquired history data on which the adaptive transform is currently dependent with other previously acquired history data, the control means being responsive to the first monitoring means. - View Dependent Claims (14, 15, 16, 17, 18, 19)
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20. An apparatus for determining a clinical state of a subject, the apparatus comprising:
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a measurement arrangement configured to acquire at least one measurement signal containing physiological data from the subject;
a signal processing unit configured to subject the measurement signal to an adaptive transform to obtain at least one transformed measurement signal, the adaptive transform being dependent on previously acquired history data;
a calculating unit configured to form a diagnostic index which is dependent on the at least one transformed measurement signal, the diagnostic index serving as a measure of the clinical state of the subject;
a monitoring unit configured to detect a predetermined event; and
a controller configured to replace at least part of the previously acquired history data on which the adaptive transform is currently dependent with other previously acquired history data, the controller being responsive to the monitoring unit.
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21. A computer program product for determining a clinical state of a subject, the computer program product comprising:
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a first program code portion configured to receive at least one measurement signal containing physiological data of a subject;
a second program code portion configured to subject the measurement signal to at least one adaptive transform, to obtain at least one transformed measurement signal, the adaptive transform being dependent on previously acquired history data;
a third program code portion configured to produce a diagnostic index which is dependent on the transformed measurement signal, the diagnostic index serving as a measure of the clinical state of the subject;
a fourth program code portion configured to detect a predetermined event; and
a fifth program code portion configured to replace at least part of the previously acquired history data on which the adaptive transform is currently dependent with other previously acquired history data, the fifth program code portion being responsive to the fourth program code portion.
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Specification