Ablation and micro-needles
First Claim
1. A device for permitting effective engagement of needles with living tissue thereby to permit for ablation of the living tissue comprising:
- a) a first substrate of flexible material having a transverse area and a peripheral edge;
b) an array of needles arranged about the area for effectively engaging the tissue;
c) a bladder related to the substrate for acting on the substrate for causing proximal ends of the needles to pass to the tissue for passage of energy associated with the needles to the tissue;
d) the area transversely within peripheral edge of the material and with which the needles are connected being for receiving the surface of the tissue with which the proximal ends of the needles are to pierce to effect a passage of energy with the needles to the tissue; and
e) a connector for a suction generator for creating a suction force in the bladder thereby to urge the tissue towards the area within the peripheral edge of the material;
the arrangement being such that suction causes the needles and tissue to move relatively closer to each other and thereby permit the proximal ends of the needles to pierce the surface of the tissue, and permit the passage of energy from the needles to the tissue, and thereby effect ablation of the tissue.
1 Assignment
0 Petitions
Accused Products
Abstract
A device permits effective engagement of micro-needles with a cutaneous layer thereby to permit for a substance to pass effectively to the cutaneous layer. A flexible or non-flexible material supports an array of micro-needles for receiving the surface of the cutaneous layer so that the proximal ends of the micro-needles pierce to effect a passage of a substance with the micro-needles to the cutaneous layer. A passageway or bladder acts on the substrate to cause the proximal ends of the micro-needles to pass to the cutaneous layer for passage of a substance associated with the micro-needles to the cutaneous layer. The bladder includes apertures located about and spaced from the micro-needles such that suction transmitted though the apertures. The micro-needles are mounted with a movable first substrate. In one form, the first substrate includes a surface with concavities and the micro-needles are mounted in the concavities, and the apertures are located in the concavities. In another form the surface is substantially flat. There can be a third layer spaced relative to the second substrate layer at least partly forming a chamber between the second layer and third layer. There can be a biasing device for urging the first substrate from the cutaneous layer.
130 Citations
55 Claims
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1. A device for permitting effective engagement of needles with living tissue thereby to permit for ablation of the living tissue comprising:
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a) a first substrate of flexible material having a transverse area and a peripheral edge;
b) an array of needles arranged about the area for effectively engaging the tissue;
c) a bladder related to the substrate for acting on the substrate for causing proximal ends of the needles to pass to the tissue for passage of energy associated with the needles to the tissue;
d) the area transversely within peripheral edge of the material and with which the needles are connected being for receiving the surface of the tissue with which the proximal ends of the needles are to pierce to effect a passage of energy with the needles to the tissue; and
e) a connector for a suction generator for creating a suction force in the bladder thereby to urge the tissue towards the area within the peripheral edge of the material;
the arrangement being such that suction causes the needles and tissue to move relatively closer to each other and thereby permit the proximal ends of the needles to pierce the surface of the tissue, and permit the passage of energy from the needles to the tissue, and thereby effect ablation of the tissue. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 26, 43, 44, 45, 51, 55)
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13. A device for permitting effective engagement of needles with living tissue thereby to permit for ablation of the living tissue comprising:
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a) a first substrate of material having a transverse area and a peripheral edge;
b) an array of needles arranged about the area for effectively engaging the tissue;
c) a passageway for transmitting suction pressure on the tissue, to cause proximal ends of the needles to pass to the tissue for passage of energy associated with the needles to the tissue;
d) the area transversely within peripheral edge of the material and with which the needles being for receiving the surface of the tissue with which the proximal ends of the needles are to pierce to effect a passage of energy with the micro needles to the tissue; and
e) a connector for a suction generator for creating a suction force thereby to urge the tissue towards the area within the peripheral edge of the material;
the arrangement being such that suction causes the needles and tissue to move relatively closer to each other and thereby permit the proximal ends of the needles to pierce the surface of the tissue, and permit the passage of energy from the needles to the tissue. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 52)
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27. A device for permitting effective engagement of needles with a living tissue thereby to permit for energy to pass effectively to the tissue comprising:
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a) a first substrate of flexible material having a transverse area and a peripheral edge;
b) an array of needles arranged about the area for effectively engaging the tissue;
c) a bladder related to the substrate for acting on the substrate for causing proximal ends of the needles to pass to the tissue for passage of energy associated with the needles to the tissue;
d) the area transversely within peripheral edge of the material and with which the needles are connected being for receiving the surface of the tissue with which the proximal ends of the needles are to engage to effect a passage of energy with the needles to the tissue; and
e) a connector for a suction generator for creating a suction force in the bladder thereby to urge the tissue towards the area within the peripheral edge of the material;
the arrangement being such that suction causes the needles and tissue to move relatively closer to each other and thereby permit the proximal ends of the needles to engage the surface of the tissue, and permit the passage of energy from the needles to the tissue. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36, 38, 39, 40, 41, 42, 46, 47, 48, 49, 50, 53)
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37. A device for penetrating living tissue to permit for interaction with the tissue and effect ablation of the tissue comprising:
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a) a first substrate of material having an area and a peripheral edge;
b) an array of needles arranged about the area for interacting with the tissue, the needles having a proximal end and a distal end;
c) selectively a spring or electromagnetic system for causing the needles to move relatively with the tissue;
d) an area transversely within peripheral edge of the material and through which the needles are directed, and the area being for receiving the surface of the tissue about which the micro needles are to interact; and
e) thereby to urge the tissue towards the area within the peripheral edge of the material and thereby provide a stabilizing force to the tissue, the arrangement being such that the needles and tissue are caused to move relatively closer to each other and thereby permit the proximal ends of the needles to interact with the surface of the tissue, and permitting the interaction of the distal end of the needle with the tissue and permit for ablation of the tissue. - View Dependent Claims (54)
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Specification