Methods and apparatus for intracranial ultrasound delivery
First Claim
1. A method for delivering ultrasound energy to a patient'"'"'s intracranial space, the method comprising:
- forming at least one hole in the patient'"'"'s skull;
advancing at least one ultrasound delivery device at least partway through the hole(s); and
transmitting ultrasound energy from the ultrasound delivery device(s).
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Accused Products
Abstract
A method for delivering ultrasound energy to a patient'"'"'s intracranial space involves forming at least one hole in the patient'"'"'s skull, advancing at least one ultrasound delivery device at least partway through the hole(s), and transmitting ultrasound energy from the ultrasound delivery device(s). According to various embodiments, ultrasound delivery devices may be advanced into the epidural space, one or both ventricles and/or an intracerebral space of the patient'"'"'s brain. In alternative embodiments, one or multiple holes may be formed in the skull, and any number of ultrasound delivery devices may be used. Intracranial ultrasound delivery may be used in treatment of ischemic stroke, head trauma, atherosclerosis, perfusion disorders and other acute or chronic neurological conditions.
39 Citations
105 Claims
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1. A method for delivering ultrasound energy to a patient'"'"'s intracranial space, the method comprising:
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forming at least one hole in the patient'"'"'s skull;
advancing at least one ultrasound delivery device at least partway through the hole(s); and
transmitting ultrasound energy from the ultrasound delivery device(s). - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 96, 97, 98, 99, 100, 101)
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36. A method for delivering ultrasound energy from within a patient'"'"'s epidural space, the method comprising:
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advancing at least one ultrasound delivery device through at least one hole in the patient'"'"'s skull to locate at least a distal portion of the device in the patient'"'"'s epidural space; and
transmitting ultrasound energy from the ultrasound delivery device(s). - View Dependent Claims (37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 102, 103)
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56. A method for delivering ultrasound energy from within at least one ventricle of a patient'"'"'s brain, the method comprising:
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advancing at least one ultrasound delivery device through at least one hole in the patient'"'"'s skull to locate at least a distal portion of the device in at least one ventricle of the patient'"'"'s brain; and
transmitting ultrasound energy from the ultrasound delivery device(s). - View Dependent Claims (57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 104)
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76. A method for delivering ultrasound energy from within an intracerebral space of a patient'"'"'s brain, the method comprising:
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advancing at least one ultrasound delivery device through at least one hole in the patient'"'"'s skull to locate at least a distal portion of the device an intracerebral space of the patient'"'"'s brain; and
transmitting ultrasound energy from the ultrasound delivery device(s). - View Dependent Claims (77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 105)
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Specification