Monofilament sutures made from a composition containing ultra high molecular weight polyethylene

• US 20070016251A1
• Filed: 07/11/2006
• Published: 01/18/2007
• Est. Priority Date: 07/13/2005
• Status: Abandoned Application

• Current Assignee: Tyco Healthcare Group LP (Medtronic Plc)
• Original Assignee: Tyco Healthcare Group LP (Medtronic Plc)
• Inventors: Roby, Mark
• Application Number:
  US11/485,590
• Publication Number:
  US 20070016251A1
• Time in Patent Office: Days
• US Class Current: 606/228
• CPC Class Codes: A61B 17/06066 Needles, e.g. needle tip configurations making needles B21G1/00
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 2017/06052 Needle-suture combinations in which a suture is extending inside a hollow tubular needle, e.g. over the entire length of the needle hollow suture needles A61B2017/061
• CPC Class Codes: A61L 17/04 Non-resorbable materials
• CPC Class Codes: A61L 17/145 Coating
• CPC Class Codes: A61L 31/048 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: C08L 23/06 Polyethene
• CPC Class Codes: C08L 23/0815 Copolymers of ethene with aliphatic 1-olefins
• CPC Class Codes: C08L 23/10 Homopolymers or copolymers of propene
• CPC Class Codes: C08L 2666/06 Homopolymers or copolymers of unsaturated hydrocarbons; Derivatives thereof

Abstract

The present disclosure provides surgical sutures made from a composition including an ultra high molecular weight polyethylene. Methods for producing such sutures and uses thereof are also provided.

Claims

1. A suture comprising a monofilament comprising an ultra high molecular weight polyethylene possessing a weight average molecular weight of greater than about 400,000.

2. The suture of claim 1, wherein the monofilament further comprises at least one other component selected from the group consisting of polyvinyl ethers, poly(phenylene ethers), acetal resins, thermoplastic polyesters, polycarbonates, cellulose esters, thermoplastic polyamides, polyetheramides, polyesteramides, thermoplastic polyurethanes, polyvinylhalides, polyvinylidene halides, halogenated polyolefins, acrylic resins, polystyrenes, polyacrylonitriles, polyvinylesters, polyimides, polyetherimides, polysulfones, and combinations thereof.

3. The suture of claim 1, wherein the ultra high molecular weight polyethylene is blended with one or more materials selected from the group consisting of polyethylenes, polypropylenes, and copolymers of polyethylene and polypropylene.

4. The suture of claim 3, wherein the polypropylene is selected from the group consisting of isotactic polypropylene, atactic polypropylene, and syndiotactic polypropylene.

5. The suture of claim 3, wherein the blend of comprises from about 5 to about 95 weight percent ultra high molecular weight polyethylene.

6. The suture of claim 1, wherein the composition comprises a copolymer of an ultra high molecular weight polyethylene with one or more monomers selected from the group consisting of isotactic polypropylene, syndiotactic polypropylene and atactic polypropylene.

7. The suture of claim 1, wherein the ultra high molecular weight polyethylene possesses a weight average molecular weight of greater than about 1,000,000.

8. The suture of claim 1, wherein the ultra high molecular weight polyethylene resin possesses a melting point of from about 144°

C. to about 152°

C.

9. The suture of claim 1, wherein the composition further comprises a fatty acid diester.

10. The suture of claim 9, wherein the fatty acid diester comprises a diester of a polyalkylene glycol.

11. The suture of claim 9, wherein the fatty acid diester comprises a polyalkylene glycol and a fatty acid selected from the group consisting of stearic acid, lauric acid, palmitic acid, myristic acid, arachidic acid, and behenic acid.

12. The suture of claim 1, further comprising a dye selected from the group consisting of carbon black, bone black, D&

C Green No. 6, and D&

C Violet No. 2.

13. The suture of claim 1, further comprising a roughened surface.

14. The suture of claim 1, further comprising a coating on at least a portion of the surface of the suture.

15. The suture of claim 14, wherein the coating is selected from the group consisting of polyolefins, polyamides, polyimides, polyethers, polyesters, polystyrenes, polyvinyl chlorides, polypropylenes, polyisoprenes, polytetrafluoroethylenes, polyurethanes, polycarbonates, and polyalkylimines optionally in combination with cross-linking agents selected from the group consisting of glutaraldehyde, glyoxal, malonaldehyde, succinaldehyde, adipaldehyde, and dialdehyde starch.

16. The suture of claim 14, wherein the coating comprises a siloxane polymer.

17. The suture of claim 16, wherein the coating comprises the product of plasma polymerization of aliphatic hydrocyclosiloxane monomers.

18. The suture of claim 17, wherein the coating further comprises amine groups.

19. The suture of claim 18, wherein the coating further comprises polyoxyalkylenes.

20. A surgical needle-suture combination comprising:

a surgical needle; and

a suture attached to the needle, the suture comprising a monofilament comprising an ultra high molecular weight polyethylene possessing a weight average molecular weight of greater than about 400,000.

21. A method of suturing a wound comprising:

providing a monofilament suture comprising an ultra high molecular weight polyethylene possessing a weight average molecular weight of greater than about 400,000 attached to a needle to form a needled suture; and

passing said needled suture through tissue to create wound closure.