Paracorporeal respiratory assist lung
First Claim
1. A paracorporeal respiratory assist lung, comprising:
- a housing having a liquid inlet, a liquid outlet, a gas inlet and a gas outlet;
a plurality of tubular gas permeable fiber membranes configured to form a fiber bundle, the fiber bundle being disposed within the housing and connected to and in fluid communication with the gas inlet and the gas outlet, wherein a first gap is configured between the housing and the fiber bundle;
a stationary core being disposed within the fiber bundle, wherein a second gap is configured between the core and the fiber bundle; and
means for rotating the fiber bundle, wherein the housing, fiber bundle and core are configured such that liquid entering the liquid inlet passes through the fiber bundle and into the liquid outlet.
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Accused Products
Abstract
A paracorporeal respiratory assist lung is configured with an annular cylindrical hollow fiber membrane (fiber bundle) that is rotated at rapidly varying speeds. Fluid (for example, blood) is introduced to the center of the device and is passed radially through the fiber bundle. The bundle is rotated at rapidly changing velocities with a rotational actuator (for example, a motor or magnetic coupling). The rotation of the fiber bundle provides centrifugal kinetic energy to the fluid giving the device pumping capabilities and may create Taylor vortexes to increase mass transfer. Rotation of the fiber bundle increases the relative velocity between the fluid and the hollow fibers and increases the mass transfer. The porosity of the fiber bundle may be varied to enhance gas exchange with the blood. Alternatively, a rotating core may be used with a stationary fiber bundle.
126 Citations
20 Claims
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1. A paracorporeal respiratory assist lung, comprising:
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a housing having a liquid inlet, a liquid outlet, a gas inlet and a gas outlet;
a plurality of tubular gas permeable fiber membranes configured to form a fiber bundle, the fiber bundle being disposed within the housing and connected to and in fluid communication with the gas inlet and the gas outlet, wherein a first gap is configured between the housing and the fiber bundle;
a stationary core being disposed within the fiber bundle, wherein a second gap is configured between the core and the fiber bundle; and
means for rotating the fiber bundle, wherein the housing, fiber bundle and core are configured such that liquid entering the liquid inlet passes through the fiber bundle and into the liquid outlet. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A paracorporeal respiratory assist lung, comprising:
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a housing having a liquid inlet, a liquid outlet, a gas inlet and a gas outlet;
a plurality of tubular gas permeable fiber membranes configured to form a fiber bundle, the fiber bundle being disposed within the housing and connected to and in fluid communication with the gas inlet and the gas outlet, wherein a first gap is configured between the housing and the fiber bundle;
a core being disposed within the fiber bundle, wherein a second gap is configured between the core and the fiber bundle; and
means for rotating the core, wherein the housing, fiber bundle and core are configured such that liquid entering the liquid inlet passes through the fiber bundle and into the liquid outlet. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A paracorporeal respiratory assist lung, comprising:
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a housing having a blood inlet, a blood outlet, a gas inlet, a gas outlet and an impeller in fluid communication with the blood inlet;
a plurality of tubular gas permeable fiber membranes configured to form a fiber bundle, the fiber bundle being disposed within the housing and connected to and in fluid communication with the gas inlet and the gas outlet, wherein a first gap is configured between the housing and the fiber bundle;
a core being disposed within the fiber bundle, wherein a second gap is configured between the core and the fiber bundle;
means for rotating the core, wherein the housing, fiber bundle and core are configured such that liquid entering the liquid inlet passes through the fiber bundle and into the liquid outlet, and wherein the means for rotating the core includes a magnetic coupling; and
a dual lumen cannula configured for insertion into the venous circulation of a patient to provide blood flow to the blood inlet of the housing and to accept blood flow from the blood outlet of the housing.
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Specification