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COMPOSITIONS AND METHODS FOR CONTROLLING ABUSE OF MEDICATIONS

  • US 20070020339A1
  • Filed: 07/20/2006
  • Published: 01/25/2007
  • Est. Priority Date: 07/20/2005
  • Status: Abandoned Application
First Claim
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1. A pharmaceutical dosage form comprising:

  • a first plurality of microcapsules, each microcapsule of the first plurality containing an opioid agonist medication in a controlled release form; and

    a second plurality of microcapsules, each microcapsule of the second plurality containing a partial opioid agonist, wherein the partial opioid agonist is provided in a sequestered form in the pharmaceutical dosage form, such that the partial opioid agonist is released in an effective amount in vivo if the pharmaceutical dosage form is administered to a person in an altered form but is not released in an effective amount in vivo if the pharmaceutical dosage form is administered to a person in a substantially unaltered form.

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