Stent vascular intervention device and methods for treating aneurysms

• US 20070021816A1
• Filed: 07/20/2006
• Published: 01/25/2007
• Est. Priority Date: 07/21/2005
• Status: Abandoned Application

• Current Assignee: The Research Foundation for The State University of New York (State University of New York)
• Original Assignee: The Research Foundation for The State University of New York (State University of New York)
• Inventors: Rudin, Stephen
• Application Number:
  US11/490,415
• Publication Number:
  US 20070021816A1
• Time in Patent Office: Days
• US Class Current: 623/1.400
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2250/0023 differing in porosity

Abstract

The present invention relates to a stent including a variable porosity, tubular structure having pores defined by structural surfaces. The tubular structure has a low porosity region in proximity to or at either end of the tubular structure, where the low porosity region is less porous than other regions located on the tubular structure and fully or partially obstructs passage of fluid. Any arcuate path that starts at one point within the low porosity region and goes around the perimeter of the tubular structure to stop at the same point within the low porosity region must have at least a portion that is outside of the low porosity region. Also disclosed is a method of modifying blood flow within and near an opening of an aneurysm in a blood vessel by deploying one or more stents of the present invention near an opening of the aneurysm in a blood vessel.

Claims

1. A stent comprising:

a variable porosity, tubular structure having pores defined by structural surfaces, said tubular structure having a low porosity region in proximity to or at either end of the tubular structure, wherein the low porosity region is less porous than other regions located on the tubular structure and fully or partially obstructs passage of fluid, the low porosity region being larger than the structural surfaces between adjacent pores, wherein any arcuate path that starts at one point within the low porosity region and goes around the perimeter of the tubular structure to stop at the same point within the low porosity region must have at least a portion that is outside of the low porosity region.

2. The stent according to claim 1, wherein the low porosity region is at either end of the tubular structure.

3. The stent according to claim 1, wherein the low porosity region is in proximity to either end of the tubular structure.

4. The stent according to claim 1, wherein said end of the tubular structure has a chamfered shape.

5. The stent according to claim 4, wherein said end of the tubular structure has a shape optimal for use inside a blood vessel and/or with another stent.

6. The stent according to claim 1, wherein all cross sectional areas of said tubular structure that are perpendicular to the longitudinal axis of the tubular structure have circular shapes with identical diameters.

7. The stent according to claim 1, wherein all cross sectional areas of said tubular structure that are perpendicular to the longitudinal axis of the tubular structure have circular shapes with variable diameters.

8. The stent according to claim 7, wherein said tubular structure has a frusto-conical shape.

9. The stent according to claim 1, wherein cross sectional areas of said tubular structure that are perpendicular to the longitudinal axis of the tubular structure have variable shapes.

10. The stent according to claim 9, wherein cross sectional areas of said tubular structure that are perpendicular to the longitudinal axis of the tubular structure have elliptical or oval shapes.

11. The stent according to claim 1, wherein the low porosity region is formed by a polymer membrane patch attached to said tubular structure.

12. The stent according to claim 11, wherein the polymer membrane patch is made of polyurethane.

13. The stent according to claim 1, wherein said tubular structure comprises a cylindrical sheet with pores of variable size or shape.

14. The stent according to claim 13, wherein said tubular structure is made of a mesh material.

15. The stent according to claim 1, wherein the low porosity region has a single pore size while all other parts of the tubular structure have another larger pore size.

16. The stent according to claim 1, wherein the low porosity region has a plurality of pore sizes with the size of the pores increasing as the low porosity region transitions to other regions of the stent.

17. The stent according to claim 1, wherein said tubular structure is formed from a plurality of strut elements which are thicker, wider, and/or denser in the low porosity region.

18. The stent according to claim 17, wherein the strut elements are made of stainless steel.

19. The stent according to claim 1, wherein the low porosity region is formed by flap-like structures in the pores.

20. The stent according to claim 1, wherein the stent is balloon expandable.

21. The stent according to claim 1, wherein the stent is self-expandable.

22. The stent according to claim 21, wherein the stent is made of a superelastic or shape memory material.

23. The stent according to claim 22, wherein the superelastic or shape memory material is nitinol.

24. The stent according to claim 1, wherein the stent is marked with, or at least partially made of, a radioopaque material imageable by high resolution radiographic imaging.

25. A method of modifying blood flow within and near an opening of an aneurysm in a blood vessel comprising:

deploying one or more stents according to claim 1 near an opening of an aneurysm in a blood vessel, so that the low porosity region of the stent causes modification of blood flow within and near the opening of the aneurysm.

26. The method according to claim 25, wherein said aneurysm is located in proximity to a vessel junction wherein one or more blood vessels split or merge into one or more blood vessels.

27. The method according to claim 26, wherein said aneurysm is located in proximity to a vessel bifurcation.

28. The method according to claim 25, wherein the low porosity region of said stent is at either end of the tubular structure.

29. The method according to claim 28, wherein said deploying comprises deploying the stent so that the low porosity region at one end of the tubular structure is proximal to the opening of the aneurysm while the other end of the tubular structure is distal to the opening of the aneurysm.

30. The method according to claim 28, wherein said deploying comprises deploying the stent so that the low porosity region at one end of the tubular structure is distal to the opening of the aneurysm while the other end of the tubular structure is proximal to the opening of the aneurysm.

31. The method according to claim 25, wherein the low porosity region of said stent is in proximity to either end of the tubular structure.

32. The method according to claim 25, wherein said deploying is performed using a balloon catheter.

33. The method according to claim 25, wherein said deploying is performed by self-expansion of the stent.

34. The method according to claim 25, wherein said deploying is guided by high resolution radiographic imaging.

35. The method according to claim 25, wherein said end of the tubular structure of said stent has a chamfered shape.

36. The method according to claim 25, wherein said end of the tubular structure of said stent has a shape optimal for use inside a blood vessel and/or with another stent.

37. The method according to claim 25, wherein all cross sectional areas of said tubular structure of said stent that are perpendicular to the longitudinal axis of the tubular structure have circular shapes with identical diameters.

38. The method according to claim 25, wherein all cross sectional areas of said tubular structure of said stent that are perpendicular to the longitudinal axis of the tubular structure have circular shapes with variable diameters.

39. The method according to claim 38, wherein said tubular structure has a frusto-conical shape.

40. The method according to claim 25, wherein cross sectional areas of said tubular structure of said stent that are perpendicular to the longitudinal axis of the tubular structure have variable shapes.

41. The method according to claim 40, wherein cross sectional areas of said tubular structure of said stent that are perpendicular to the longitudinal axis of the tubular structure have elliptical or oval shapes.

42. The method according to claim 25, wherein the low porosity region of said stent is formed by a polymer membrane patch attached to said tubular structure.

43. The method according to claim 42, wherein the polymer membrane patch is made of polyurethane.

44. The method according to claim 25, wherein the tubular structure of said stent comprises a cylindrical sheet with pores of variable size or shape.

45. The method according to claim 44, wherein said tubular structure is made of a mesh material.

46. The method according to claim 25, wherein the low porosity region of said stent has a single pore size while all other parts of the tubular structure of said stent have another larger pore size.

47. The method according to claim 25, wherein the low porosity region of said stent has a plurality of pore sizes with the size of the pores increasing as the low porosity region transitions to other regions of the stent.

48. The method according to claim 25, wherein the tubular structure of said stent is formed from a plurality of strut elements which are thicker, wider, and/or denser in the low porosity region.

49. The method according to claim 48, wherein the strut elements are made of stainless steel.

50. The method according to claim 25, wherein the low porosity region of said stent is formed by flap-like structures in the pores.