Method and apparatus for syringe-based sample introduction within a flow cytometer
First Claim
1. An apparatus for introducing a specimen into a flow cytometer, the apparatus comprising:
- a syringe having a hollow barrel containing the specimen, a plunger partially within the barrel and a needle that extends into a volume of a nozzle of the flow cytometer;
a one-way port in the nozzle forming a seal against the needle;
a mounting platform coupled to both the syringe and to the flow cytometer; and
a syringe pump coupled to the plunger and comprising;
a motor, a drive mechanism coupled to the motor; and
a clamping mechanism coupled to the drive mechanism and to an element of the group consisting of the syringe barrel, the mounting platform and the flow cytometer, wherein the motor operates the drive mechanism so as to cause the clamping mechanism to depress the plunger into the barrel.
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Accused Products
Abstract
An apparatus for introducing a specimen into a flow cytometer comprises: a syringe having a hollow barrel containing the specimen, a plunger partially within the barrel and a needle that extends into a volume of a nozzle of the flow cytometer; a one-way port in the nozzle forming a seal against the needle; a mounting platform coupled to both the syringe and to the flow cytometer; and a syringe pump coupled to the plunger, the syringe pump comprising a motor, a drive mechanism coupled to the motor; and a clamping mechanism coupled to the drive mechanism, wherein the motor operates the drive mechanism so as to cause the clamping mechanism to depress the plunger into the barrel.
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Citations
20 Claims
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1. An apparatus for introducing a specimen into a flow cytometer, the apparatus comprising:
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a syringe having a hollow barrel containing the specimen, a plunger partially within the barrel and a needle that extends into a volume of a nozzle of the flow cytometer;
a one-way port in the nozzle forming a seal against the needle;
a mounting platform coupled to both the syringe and to the flow cytometer; and
a syringe pump coupled to the plunger and comprising;
a motor, a drive mechanism coupled to the motor; and
a clamping mechanism coupled to the drive mechanism and to an element of the group consisting of the syringe barrel, the mounting platform and the flow cytometer, wherein the motor operates the drive mechanism so as to cause the clamping mechanism to depress the plunger into the barrel. - View Dependent Claims (2, 3, 4, 5, 11, 12, 13)
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6. An apparatus for introducing a specimen into a flow cytometer, the apparatus comprising:
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a syringe having a hollow barrel containing the specimen, a plunger partially within the barrel and a needle that extends into a volume of a nozzle of the flow cytometer;
a hollow receptacle in the nozzle receiving and forming a seal against the needle;
a mounting platform coupled to both the syringe and to the flow cytometer; and
a syringe pump coupled to the plunger and comprising;
a motor, a drive mechanism coupled to the motor; and
a clamping mechanism coupled to the drive mechanism and to an element of the group consisting of the barrel, the mounting platform and the flow cytometer, wherein the motor operates the drive mechanism so as to cause the clamping mechanism to depress the plunger into the barrel. - View Dependent Claims (7, 8, 9, 10)
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14. A method for introducing a specimen into a flow cytometer comprises the steps of:
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providing a syringe having a hollow barrel containing the specimen, a plunger partially within the barrel and a needle extending into a volume of a nozzle of the flow cytometer;
providing a one-way port in the nozzle container forming a seal against the needle;
providing a mounting platform coupled to both the syringe and to the flow cytometer;
providing a syringe pump coupled to the plunger and comprising;
a motor;
a drive mechanism coupled to the motor; and
a clamping mechanism coupled to the drive mechanism and to an element of the group consisting of the barrel, the mounting platform and the flow cytometer; and
operating the motor so as to operate the drive mechanism so as to cause the clamping mechanism to depress the plunger into the barrel. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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Specification